activity
19942016
most citedDistinct changes of genomic biases in nucleotide substitution at the time of mammalian radiation

108 citations · 542 across the 16 of their papers we have counts for

collaborators

16 papers

q-bio.PE2016★ 11 cited

Evolutionary dynamics of selfish DNA generates pseudo-linguistic features of genomes

Michael Sheinman, Anna Ramisch, Florian Massip +1

Since the sequencing of large genomes, many statistical features of their sequences have been found. One intriguing feature is that certain subsequences are much more abundant than…

q-bio.PE2014★ 8 cited

Statistical Properties of Pairwise Distances between Leaves on a Random Yule Tree

Michael Sheinman, Florian Massip, Peter F. Arndt

A Yule tree is the result of a branching process with constant birth and death rates. Such a process serves as an instructive null model of many empirical systems, for instance, th…

q-bio.GN2005

Substantial regional variation in substitution rates in the human genome: importance of GC content, gene density and telomere-specific effects

Peter F Arndt, Terence Hwa, Dmitri A Petrov

This study presents the first global, 1 Mbp level analysis of patterns of nucleotide substitutions along the human lineage. The study is based on the analysis of a large amount of…

q-bio.GN2005

Identification and Measurement of Neighbor Dependent Nucleotide Substitution Processes

Peter F. Arndt, Terence Hwa

The presence of neighbor dependencies generated a specific pattern of dinucleotide frequencies in all organisms. Especially, the CpG-methylation-deamination process is the predomin…

q-bio.GN2005★ 55 cited

A Solvable Sequence Evolution Model and Genomic Correlations

Philipp W. Messer, Peter F. Arndt, Michael Lässig

We study a minimal model for genome evolution whose elementary processes are single site mutation, duplication and deletion of sequence regions and insertion of random segments. Th…

cond-mat.stat-mech2003★ 108 cited

Distinct changes of genomic biases in nucleotide substitution at the time of mammalian radiation

Peter F. Arndt, Dmitri A. Petrov, Terence Hwa

Differences in the regional substitution patterns in the human genome created patterns of large-scale variation of base composition known as genomic isochores. To gain insight into…