108 citations · 163 across the 4 of their papers we have counts for
6 papers
Substantial regional variation in substitution rates in the human genome: importance of GC content, gene density and telomere-specific effects
Peter F Arndt, Terence Hwa, Dmitri A Petrov
This study presents the first global, 1 Mbp level analysis of patterns of nucleotide substitutions along the human lineage. The study is based on the analysis of a large amount of…
Identification and Measurement of Neighbor Dependent Nucleotide Substitution Processes
Peter F. Arndt, Terence Hwa
The presence of neighbor dependencies generated a specific pattern of dinucleotide frequencies in all organisms. Especially, the CpG-methylation-deamination process is the predomin…
A Solvable Sequence Evolution Model and Genomic Correlations
Philipp W. Messer, Peter F. Arndt, Michael Lässig
We study a minimal model for genome evolution whose elementary processes are single site mutation, duplication and deletion of sequence regions and insertion of random segments. Th…
Distinct changes of genomic biases in nucleotide substitution at the time of mammalian radiation
Peter F. Arndt, Dmitri A. Petrov, Terence Hwa
Differences in the regional substitution patterns in the human genome created patterns of large-scale variation of base composition known as genomic isochores. To gain insight into…
DNA Sequence Evolution with Neighbor-Dependent Mutation
Peter F. Arndt, Christopher B. Burge, Terence Hwa
We introduce a model of DNA sequence evolution which can account for biases in mutation rates that depend on the identity of the neighboring bases. An analytic solution for this cl…
Spontaneous Breaking of Translational Invariance and Spatial Condensation in Stationary States on a Ring: II. The Charged System and the Two-component Burgers Equations
Peter F. Arndt, Vladimir Rittenberg
We further study the stochastic model discussed in Ref.[2] in which positive and negative particles diffuse in an asymmetric, CP invariant way on a ring. The positive particles hop…