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20102026
most citedDirect-coupling analysis of residue co-evolution captures native contacts across many protein families

1.6k citations

Showing 2016Show all

17 papers · 1 filter

cond-mat.dis-nn2016★ 79 cited

Numerical estimate of the Kardar Parisi Zhang universality class in (2 + 1) dimensions

Andrea Pagnani, Giorgio Parisi

We study the Restricted Solid on Solid model for surface growth in spatial dimension by means of a multi-surface coding technique that allows to produce a large number of sam…

q-bio.MN2016

On the role of extrinsic noise in microRNA-mediated bimodal gene expression

Marco Del Giudice, Stefano Bo, Silvia Grigolon +1

Several studies highlighted the relevance of extrinsic noise in shaping cell decision making and differentiation in molecular networks. Experimental evidences of phenotypic differe…

cond-mat.dis-nn2016★ 10 cited

One-loop diagrams in the Random Euclidean Matching Problem

Carlo Lucibello, Giorgio Parisi, Gabriele Sicuro

The matching problem is a notorious combinatorial optimization problem that has attracted for many years the attention of the statistical physics community. Here we analyze the Euc…

physics.soc-ph2016★ 30 cited

Network reconstruction from infection cascades

Alfredo Braunstein, Alessandro Ingrosso, Anna Paola Muntoni

Accessing the network through which a propagation dynamics diffuse is essential for understanding and controlling it. In a few cases, such information is available through direct e…

physics.soc-ph2016★ 6 cited

Predicting epidemic evolution on contact networks from partial observations

Jacopo Bindi, Alfredo Braunstein, Luca Dall'Asta

The massive employment of computational models in network epidemiology calls for the development of improved inference methods for epidemic forecast. For simple compartment models,…

cond-mat.stat-mech2016★ 4 cited

A method to reduce the rejection rate in Monte Carlo Markov Chains

Carlo Baldassi

We present a method for Monte Carlo sampling on systems with discrete variables (focusing in the Ising case), introducing a prior on the candidate moves in a Metropolis-Hastings sc…

cs.DS2016★ 1 cited

Practical optimization of Steiner Trees via the cavity method

Alfredo Braunstein, Anna Muntoni

The optimization version of the cavity method for single instances, called Max-Sum, has been applied in the past to the Minimum Steiner Tree Problem on Graphs and variants. Max-Sum…

cond-mat.dis-nn2016★ 5 cited

Inverse problem for multi-body interaction of nonlinear waves

Alessia Marruzzo, Payal Tyagi, Fabrizio Antenucci +2

The inverse problem is studied in multi-body systems with nonlinear dynamics representing, e.g., phase-locked wave systems, standard multimode and random lasers. Using a general mo…

q-bio.MN2016★ 193 cited

Constrained Allocation Flux Balance Analysis

Matteo Mori, Terence Hwa, Olivier C. Martin +2

New experimental results on bacterial growth inspire a novel top-down approach to study cell metabolism, combining mass balance and proteomic constraints to extend and complement F…

q-bio.QM2016★ 148 cited

Simultaneous identification of specifically interacting paralogs and inter-protein contacts by Direct-Coupling Analysis

Thomas Gueudré, Carlo Baldassi, Marco Zamparo +2

Understanding protein-protein interactions is central to our understanding of almost all complex biological processes. Computational tools exploiting rapidly growing genomic databa…

stat.ML2016★ 149 cited

Unreasonable Effectiveness of Learning Neural Networks: From Accessible States and Robust Ensembles to Basic Algorithmic Schemes

Carlo Baldassi, Christian Borgs, Jennifer Chayes +4

In artificial neural networks, learning from data is a computationally demanding task in which a large number of connection weights are iteratively tuned through stochastic-gradien…

q-bio.MN2016★ 14 cited

Noise Processing by MicroRNA-Mediated Circuits: the Incoherent Feed-Forward Loop, Revisited

Silvia Grigolon, Francesca Di Patti, Andrea De Martino +1

The intrinsic stochasticity of gene expression is usually mitigated in higher eukaryotes by post-transcriptional regulation channels that stabilise the output layer, most notably p…

cond-mat.dis-nn2016★ 10 cited

Regularization and decimation pseudolikelihood approaches to statistical inference in -spin models

Payal Tyagi, Alessia Marruzzo, Andrea Pagnani +2

We implement a pseudolikelyhood approach with l2-regularization as well as the recently introduced pseudolikelihood with decimation procedure to the inverse problem in continuous s…

physics.soc-ph2016★ 304 cited

Network dismantling

Alfredo Braunstein, Luca Dall'Asta, Guilhem Semerjian +1

We study the network dismantling problem, which consists in determining a minimal set of vertices whose removal leaves the network broken into connected components of sub-extensive…

cond-mat.dis-nn2016★ 24 cited

Learning may need only a few bits of synaptic precision

Carlo Baldassi, Federica Gerace, Carlo Lucibello +2

Learning in neural networks poses peculiar challenges when using discretized rather then continuous synaptic states. The choice of discrete synapses is motivated by biological reas…

cond-mat.dis-nn2016★ 20 cited

The large deviations of the whitening process in random constraint satisfaction problems

Alfredo Braunstein, Luca Dall'Asta, Guilhem Semerjian +1

Random constraint satisfaction problems undergo several phase transitions as the ratio between the number of constraints and the number of variables is varied. When this ratio exce…

q-bio.MN2016★ 50 cited

Growth against entropy in bacterial metabolism: the phenotypic trade-off behind empirical growth rate distributions in E. coli

Daniele De Martino, Fabrizio Capuani, Andrea De Martino

The solution space of genome-scale models of cellular metabolism provides a map between physically viable flux configurations and cellular metabolic phenotypes described, at the mo…