193 citations · 218 across the 4 of their papers we have counts for
4 papers
Independent channels for miRNA biosynthesis ensure efficient static and dynamic control in the regulation of the early stages of myogenesis
Jonathan Fiorentino, Andrea De Martino
Motivated by recent experimental work, we define and study a deterministic model of the complex miRNA-based regulatory circuit that putatively controls the early stage of myogenesi…
Kinetic modelling of competition and depletion of shared miRNAs by competing endogenous RNAs
Araks Martirosyan, Marco Del Giudice, Chiara Enrico Bena +3
Non-conding RNAs play a key role in the post-transcriptional regulation of mRNA translation and turnover in eukaryotes. miRNAs, in particular, interact with their target RNAs throu…
Constrained Allocation Flux Balance Analysis
Matteo Mori, Terence Hwa, Olivier C. Martin +2
New experimental results on bacterial growth inspire a novel top-down approach to study cell metabolism, combining mass balance and proteomic constraints to extend and complement F…
Quantitative constraint-based computational model of tumor-to-stroma coupling via lactate shuttle
Fabrizio Capuani, Daniele De Martino, Enzo Marinari +1
Cancer cells utilize large amounts of ATP to sustain growth, relying primarily on non-oxidative, fermentative pathways for its production. In many types of cancers this leads, even…