41 citations · 126 across the 9 of their papers we have counts for
9 papers
Path-integral solution of MacArthur's resource-competition model for large ecosystems with random species-resources couplings
A. R. Batista-Tomas, Andrea De Martino, Roberto Mulet
We solve MacArthur's resource-competition model with random species-resource couplings in the `thermodynamic' limit of infinitely many species and resources using dynamical path-in…
Exploration-exploitation tradeoffs dictate the optimal distributions of phenotypes for populations subject to fitness fluctuations
Andrea De Martino, Thomas Gueudré, Mattia Miotto
We study a minimal model for the growth of a phenotypically heterogeneous population of cells subject to a fluctuating environment in which they can replicate (by exploiting availa…
ceRNA crosstalk stabilizes protein expression and affects the correlation pattern of interacting proteins
Araks Martirosyan, Andrea De Martino, Andrea Pagnani +1
Gene expression is a noisy process and several mechanisms, both transcriptional and posttranscriptional, can stabilize protein levels in cells. Much work has focused on the role of…
A yield-cost tradeoff governs Escherichia coli's decision between fermentation and respiration in carbon-limited growth
Matteo Mori, Enzo Marinari, Andrea De Martino
Many microbial systems are known to actively reshape their proteomes in response to changes in growth conditions induced e.g. by nutritional stress or antibiotics. Part of the re-a…
Noise Processing by MicroRNA-Mediated Circuits: the Incoherent Feed-Forward Loop, Revisited
Silvia Grigolon, Francesca Di Patti, Andrea De Martino +1
The intrinsic stochasticity of gene expression is usually mitigated in higher eukaryotes by post-transcriptional regulation channels that stabilise the output layer, most notably p…
Identifying essential genes in E. coli from a metabolic optimization principle
C. Martelli, A. De Martino, E. Marinari +2
Understanding the organization of reaction fluxes in cellular metabolism from the stoichiometry and the topology of the underlying biochemical network is a central issue in systems…