159 citations · 924 across the 18 of their papers we have counts for
8 papers · 1 filter
Compression and stretching of a self-avoiding chain in cylindrical nanopores
Suckjoon Jun, D. Thirumalai, Bae-Yeun Ha
Force-induced deformations of a self-avoiding chain confined inside a cylindrical cavity, with diameter , are probed using molecular dynamics simulations, scaling analysis, and…
Force Dependent Hopping Rates of RNA Hairpins can be Estimated from Accurate Measurement of the Folding Landscapes
Changbong Hyeon, Greg Morrison, D. Thirumalai
The sequence-dependent folding landscapes of nucleic acid hairpins reflect much of the complexity of biomolecular folding. Folding trajectories, generated using single molecule for…
Stretching Homopolymers
Greg Morrison, Changbong Hyeon, N. M. Toan +2
Force induced stretching of polymers is important in a variety of contexts. We have used theory and simulations to describe the response of homopolymers, with monomers, to forc…
Measuring the energy landscape roughness and the transition state location of biomolecules using single molecule mechanical unfolding experiments
Changbong Hyeon, D. Thirumalai
Single molecule mechanical unfolding experiments are beginning to provide profiles of the complex energy landscape of biomolecules. In order to obtain reliable estimates of the ene…
Dependence of folding rates on protein length
Mai Suan Li, D. K. Klimov, D. Thirumalai
Using three-dimensional Go lattice models with side chains for proteins, we investigate the dependence of folding times on protein length. In agreement with previous theoretical pr…
Introducing Protein Folding Using Simple Models
D. Thirumalai, D. K. Klimov
We discuss recent theoretical developments in the study of simple lattice models of proteins. Such models are designed to understand general features of protein structures and mech…