100 citations · 292 across the 14 of their papers we have counts for
5 papers · 1 filter
Monovalent ions modulate the flux through multiple folding pathways of an RNA pseudoknot
Jorjethe Roca, Naoto Hori, Yogambigai Velmurugu +4
The functions of RNA pseudoknots (PKs), which are minimal tertiary structural motifs and an integral part of several ribozymes and ribonucleoprotein complexes, are determined by th…
Folding PDZ2 domain using the Molecular Transfer Model
Zhenxing Liu, Govardhan Reddy, D. Thirumalai
A major challenge in molecular simulations is to describe denaturant-dependent folding of proteins order to make direct comparisons with {\it in vitro} experiments. We use the mole…
Force-Induced Unzipping Transitions in an Athermal Crowded Environment
David L. Pincus, D. Thirumalai
Using theoretical arguments and extensive Monte Carlo (MC) simulations of a coarse-grained three-dimensional off-lattice model of a β-hairpin, we demonstrate that the equilibrium c…
Entropic Stabilization of Proteins by TMAO
Samuel S. Cho, Govardhan Reddy, John E. Straub +1
To understand the mechanism of trimethylamine N-oxide (TMAO) induced stabilization of folded protein states, we systematically investigated the action of TMAO on several model dipe…
How accurate are polymer models in the analysis of Forster resonance energy transfer experiments on proteins?
E. P. O'Brien, G. Morrison, B. R. Brooks +1
Single molecule Forster resonance energy transfer (FRET) experiments are used to infer the properties of the denatured state ensemble (DSE) of proteins. From the measured average F…