165 citations · 1.3k across the 51 of their papers we have counts for
24 papers · 1 filter
Effects of cell-cell communication on bacterial chemotaxis
Soutick Saha, Sean Fancher, Andrew Mugler
Bacteria track chemical gradients using a biased random walk, a process called chemotaxis. Experiments suggest that bacteria also communicate during this process. Using a mathemati…
Exosome-mediated chemotaxis optimizes leader-follower cell migration
Louis González, Andrew Mugler
Cells frequently employ extracellular vesicles, or exosomes, to signal across long distances and coordinate collective actions. Exosomes diffuse slowly, can be actively degraded, a…
Near-critical gene expression in embryonic boundary precision
Michael Vennettilli, Krishna P. Ramachandran, Andrew Mugler
Embryonic development relies on the formation of sharp, precise gene expression boundaries. In the fruit fly Drosophila melanogaster, boundary formation has been proposed to occur…
Quantifying cellular autonomy in multi-cue environments
Louis Gonzalez, Hogyeong Gwak, Bumsoo Han +1
A cell routinely responds to one of many competing environmental cues. A fundamental question is whether the cell follows the cue prioritized by its internal signaling network or t…
Collective effects in flow-driven cell migration
Louis González, Andrew Mugler
Autologous chemotaxis is the process in which cells secrete and detect molecules to determine the direction of fluid flow. Experiments and theory suggest that autologous chemotaxis…
Effects of molecular noise on cell size control
Motasem ElGamel, Andrew Mugler
Cells employ control strategies to maintain a stable size. Dividing at a target size (the `sizer' strategy) is thought to produce the tightest size distribution. However, this resu…