165 citations · 1.3k across the 51 of their papers we have counts for
4 papers · 1 filter
Physical constraints on accuracy and persistence during breast cancer cell chemotaxis
Julien Varennes, Hye-ran Moon, Soutick Saha +2
Directed cell motion in response to an external chemical gradient occurs in many biological phenomena such as wound healing, angiogenesis, and cancer metastasis. Chemotaxis is ofte…
Dynamic sampling and information encoding in biochemical networks
Garrett D. Potter, Tommy A. Byrd, Andrew Mugler +1
Cells use biochemical networks to translate environmental information into intracellular responses. These responses can be highly dynamic, but how the information is encoded in the…
Cell-cell communication enhances the capacity of cell ensembles to sense shallow gradients during morphogenesis
David Ellison, Andrew Mugler, Matthew Brennan +9
Collective cell responses to exogenous cues depend on cell-cell interactions. In principle, these can result in enhanced sensitivity to weak and noisy stimuli. However, this has no…
Communication shapes sensory response in multicellular networks
Garrett D Potter, Tommy A Byrd, Andrew Mugler +1
Collective sensing by interacting cells is observed in a variety of biological systems, and yet a quantitative understanding of how sensory information is collectively encoded is l…