activity
20082025
most citedCell-cell communication enhances the capacity of cell ensembles to sense shallow gradients during morphogenesis

165 citations · 1.3k across the 51 of their papers we have counts for

collaborators

52 papers

physics.bio-ph2025

Effects of cell-cell communication on bacterial chemotaxis

Soutick Saha, Sean Fancher, Andrew Mugler

Bacteria track chemical gradients using a biased random walk, a process called chemotaxis. Experiments suggest that bacteria also communicate during this process. Using a mathemati…

physics.bio-ph2025

Exosome-mediated chemotaxis optimizes leader-follower cell migration

Louis González, Andrew Mugler

Cells frequently employ extracellular vesicles, or exosomes, to signal across long distances and coordinate collective actions. Exosomes diffuse slowly, can be actively degraded, a…

physics.bio-ph2025

Near-critical gene expression in embryonic boundary precision

Michael Vennettilli, Krishna P. Ramachandran, Andrew Mugler

Embryonic development relies on the formation of sharp, precise gene expression boundaries. In the fruit fly Drosophila melanogaster, boundary formation has been proposed to occur…

physics.bio-ph2024

Quantifying cellular autonomy in multi-cue environments

Louis Gonzalez, Hogyeong Gwak, Bumsoo Han +1

A cell routinely responds to one of many competing environmental cues. A fundamental question is whether the cell follows the cue prioritized by its internal signaling network or t…

physics.bio-ph2023

Collective effects in flow-driven cell migration

Louis González, Andrew Mugler

Autologous chemotaxis is the process in which cells secrete and detect molecules to determine the direction of fluid flow. Experiments and theory suggest that autologous chemotaxis…

physics.bio-ph2023

Effects of molecular noise on cell size control

Motasem ElGamel, Andrew Mugler

Cells employ control strategies to maintain a stable size. Dividing at a target size (the `sizer' strategy) is thought to produce the tightest size distribution. However, this resu…