165 citations · 1.3k across the 51 of their papers we have counts for
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Prediction and Dissipation in Biochemical Sensing
Nils B. Becker, Andrew Mugler, Pieter Rein ten Wolde
Cells sense and predict their environment via energy-dissipating pathways. However, it is unclear whether dissipation helps or harms prediction. Here we study dissipation and predi…
The importance of crowding in signaling, genetic, and metabolic networks
Pieter Rein ten Wolde, Andrew Mugler
It is now well established that the cell is a highly crowded environment. Yet, the effects of crowding on the dynamics of signaling pathways, gene regulation networks and metabolic…
Spatial partitioning improves the reliability of biochemical signaling
Andrew Mugler, Filipe Tostevin, Pieter Rein ten Wolde
Spatial heterogeneity is a hallmark of living systems, even at the molecular scale in individual cells. A key example is the partitioning of membrane-bound proteins via lipid domai…