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20032026
most citedGPU-based Low Dose CT Reconstruction via Edge-preserving Total Variation Regularization

399 citations

Showing 2020 · stat.MEShow all

5 papers · 2 filters

stat.ME2020★ 1 cited

Optimal Bayesian hierarchical model to accelerate the development of tissue-agnostic drugs and basket trials

Liyun Jiang, Lei Nie, Fangrong Yan +1

Tissue-agnostic trials enroll patients based on their genetic biomarkers, not tumor type, in an attempt to determine if a new drug can successfully treat disease conditions based o…

stat.ME2020★ 11 cited

A Note on Bayesian Modeling Specification of Censored Data in JAGS

Xinyue Qi, Shouhao Zhou, Martyn Plummer

Just Another Gibbs Sampling (JAGS) is a convenient tool to draw posterior samples using Markov Chain Monte Carlo for Bayesian modeling. However, the built-in function dinterval() t…

stat.ME2020★ 2 cited

A Framework for Mediation Analysis with Multiple Exposures, Multivariate Mediators, and Non-Linear Response Models

James P. Long, Ehsan Irajizad, James D. Doecke +2

Mediation analysis seeks to identify and quantify the paths by which an exposure affects an outcome. Intermediate variables which are effected by the exposure and which effect the…

stat.ME2020★ 5 cited

Elastic Priors to Dynamically Borrow Information from Historical Data in Clinical Trials

Liyun Jiang, Lei Nie, Ying Yuan

Use of historical data and real-world evidence holds great potential to improve the efficiency of clinical trials. One major challenge is how to effectively borrow information from…

stat.ME2020★ 1 cited

Design of phase III trials with long-term survival outcomes based on short-term binary results

Marta Bofill Roig, Yu Shen, Guadalupe Gómez Melis

Pathologic complete response (pCR) is a common primary endpoint for a phase II trial or even accelerated approval of neoadjuvant cancer therapy. If granted, a two-arm confirmatory…