most citedPrincipal Stratum Strategy: Potential Role in Drug Development

68 citations

researchers with a paper here

Counting papers with at most 25 authors, so collaboration author lists do not stand in for the people here.

collaborating institutions

3 papers

stat.ME2024★ 2 cited

Balancing events, not patients, maximizes power of the logrank test: and other insights on unequal randomization in survival trials

Godwin Yung, Kaspar Rufibach, Marcel Wolbers +2

We revisit the question of what randomization ratio (RR) maximizes power of the logrank test in event-driven survival trials under proportional hazards (PH). By comparing three app…

stat.AP2020★ 68 cited

Principal Stratum Strategy: Potential Role in Drug Development

Björn Bornkamp, Kaspar Rufibach, Jianchang Lin +6

A randomized trial allows estimation of the causal effect of an intervention compared to a control in the overall population and in subpopulations defined by baseline characteristi…

q-bio.OT2020★ 36 cited

Assessing the Impact of COVID-19 on the Objective and Analysis of Oncology Clinical Trials -- Application of the Estimand Framework

Evgeny Degtyarev, Kaspar Rufibach, Yue Shentu +10

COVID-19 outbreak has rapidly evolved into a global pandemic. The impact of COVID-19 on patient journeys in oncology represents a new risk to interpretation of trial results and it…