36 citations
- AbbVie (Germany)DE1 paper
- Berry & Associates (United States)US1 paper
- Biogen (United States)US1 paper
- Boehringer Ingelheim (Germany)DE1 paper
- Fred Hutch Cancer CenterUS1 paper
- GlaxoSmithKline (United States)US1 paper
- Google (United States)US1 paper
- Janssen Research & Development (United States)US1 paper
- Massachusetts Institute of TechnologyUS1 paper
- Medical University of ViennaAT1 paper
- Merck & Co., Inc., Rahway, NJ, USA (United States)US1 paper
- Michigan State UniversityUS1 paper
6 papers
Noether invariance theory for the equilibrium force structure of soft matter
Sophie Hermann, Florian Sammüller, Matthias Schmidt
We give details and derivations for the Noether invariance theory that characterizes the spatial equilibrium structure of inhomogeneous classical many-body systems, as recently pro…
Use of Non-concurrent Common Control in Master Protocols in Oncology Trials: Report of an American Statistical Association Biopharmaceutical Section Open Forum Discussion
Rajeshwari Sridhara, Olga Marchenko, Qi Jiang +14
This article summarizes the discussions from the American Statistical Association (ASA) Biopharmaceutical (BIOP) Section Open Forum that took place on December 10, 2020 and was org…
NADE: A Benchmark for Robust Adverse Drug Events Extraction in Face of Negations
Simone Scaboro, Beatrice Portelli, Emmanuele Chersoni +2
Adverse Drug Event (ADE) extraction models can rapidly examine large collections of social media texts, detecting mentions of drug-related adverse reactions and trigger medical inv…
Exploring a Unified Sequence-To-Sequence Transformer for Medical Product Safety Monitoring in Social Media
Shivam Raval, Hooman Sedghamiz, Enrico Santus +3
Adverse Events (AE) are harmful events resulting from the use of medical products. Although social media may be crucial for early AE detection, the sheer scale of this data makes i…
Assessing the Impact of COVID-19 on the Objective and Analysis of Oncology Clinical Trials -- Application of the Estimand Framework
Evgeny Degtyarev, Kaspar Rufibach, Yue Shentu +10
COVID-19 outbreak has rapidly evolved into a global pandemic. The impact of COVID-19 on patient journeys in oncology represents a new risk to interpretation of trial results and it…
Cubature on Wiener space in infinite dimension
Christian Bayer, Josef Teichmann
We prove a stochastic Taylor expansion for SPDEs and apply this result to obtain cubature methods, i. e. high order weak approximation schemes for SPDEs, in the spirit of T. Lyons…