output
20132020
most citedModel-based dose finding under model uncertainty using general parametric models

165 citations

researchers with a paper here

Counting papers with at most 25 authors, so collaboration author lists do not stand in for the people here.

collaborating institutions

3 papers

q-bio.OT2020★ 36 cited

Assessing the Impact of COVID-19 on the Objective and Analysis of Oncology Clinical Trials -- Application of the Estimand Framework

Evgeny Degtyarev, Kaspar Rufibach, Yue Shentu +10

COVID-19 outbreak has rapidly evolved into a global pandemic. The impact of COVID-19 on patient journeys in oncology represents a new risk to interpretation of trial results and it…

stat.AP2019★ 112 cited

Alternative Analysis Methods for Time to Event Endpoints under Non-proportional Hazards: A Comparative Analysis

Ray S. Lin, Ji Lin, Satrajit Roychoudhury +16

The log-rank test is most powerful under proportional hazards (PH). In practice, non-PH patterns are often observed in clinical trials, such as in immuno-oncology; therefore, alter…

stat.ME2013★ 165 cited

Model-based dose finding under model uncertainty using general parametric models

José Pinheiro, Björn Bornkamp, Ekkehard Glimm +1

Statistical methodology for the design and analysis of clinical Phase II dose response studies, with related software implementation, are well developed for the case of a normally…