112 citations
- Academia SinicaTW1 paper
- Bristol-Myers Squibb (United States)US1 paper
- Cape Town HVTN Immunology Laboratory / Hutchinson Centre Research Institute of South AfricaZA1 paper
- Celgene (United States)US1 paper
- Eli Lilly (United States)US1 paper
- Fred Hutch Cancer CenterUS1 paper
- Genesys (United States)US1 paper
- Institute of Statistical Science, Academia SinicaTW1 paper
- Janssen Research & Development (United States)US1 paper
- Ludwig-Maximilians-Universität MünchenDE1 paper
- Merck & Co., Inc., Rahway, NJ, USA (United States)US1 paper
- National Research University Higher School of EconomicsRU1 paper
7 papers
Kidney segmentation using 3D U-Net localized with Expectation Maximization
Omid Bazgir, Kai Barck, Richard A. D. Carano +2
Kidney volume is greatly affected in several renal diseases. Precise and automatic segmentation of the kidney can help determine kidney size and evaluate renal function. Fully conv…
Alternative Analysis Methods for Time to Event Endpoints under Non-proportional Hazards: A Comparative Analysis
Ray S. Lin, Ji Lin, Satrajit Roychoudhury +16
The log-rank test is most powerful under proportional hazards (PH). In practice, non-PH patterns are often observed in clinical trials, such as in immuno-oncology; therefore, alter…
Survival Forests under Test: Impact of the Proportional Hazards Assumption on Prognostic and Predictive Forests for ALS Survival
Natalia Korepanova, Heidi Seibold, Verena Steffen +1
We investigate the effect of the proportional hazards assumption on prognostic and predictive models of the survival time of patients suffering from amyotrophic lateral sclerosis (…
trackr: A Framework for Enhancing Discoverability and Reproducibility of Data Visualizations and Other Artifacts in R
Gabriel Becker, Sara E. Moore, Michael Lawrence
Research is an incremental, iterative process, with new results relying and building upon previous ones. Scientists need to find, retrieve, understand, and verify results in order…
A Critical Survey of Deconvolution Methods for Separating cell-types in Complex Tissues
Shahin Mohammadi, Neta Zuckerman, Andrea Goldsmith +1
Identifying concentrations of components from an observed mixture is a fundamental problem in signal processing. It has diverse applications in fields ranging from hyperspectral im…
Scalable Genomics with R and Bioconductor
Michael Lawrence, Martin Morgan
This paper reviews strategies for solving problems encountered when analyzing large genomic data sets and describes the implementation of those strategies in R by packages from the…