35 citations
- 1QBit1 paper
- Accenture (United States)US1 paper
- Bayer (United States)US1 paper
- Berry & Associates (United States)US1 paper
- Duke Medical CenterUS1 paper
- Duke UniversityUS1 paper
- Fred Hutch Cancer CenterUS1 paper
- Harvard UniversityUS1 paper
- Health and Human Development (2HD) Research NetworkCM1 paper
- McGill UniversityCA1 paper
- Medical University of ViennaAT1 paper
- Radboud University Medical CenterNL1 paper
5 papers
Use of Non-concurrent Common Control in Master Protocols in Oncology Trials: Report of an American Statistical Association Biopharmaceutical Section Open Forum Discussion
Rajeshwari Sridhara, Olga Marchenko, Qi Jiang +14
This article summarizes the discussions from the American Statistical Association (ASA) Biopharmaceutical (BIOP) Section Open Forum that took place on December 10, 2020 and was org…
Evaluating hybrid controls methodology in early-phase oncology trials: a simulation study based on the MORPHEUS-UC trial
Guanbo Wang, Melanie Poulin Costello, Herbert Pang +6
Phase Ib/II oncology trials, despite their small sample sizes, aim to provide information for optimal internal company decision-making concerning novel drug development. Hybrid con…
A Quantum-Inspired Method for Three-Dimensional Ligand-Based Virtual Screening
Maritza Hernandez, Guo Liang Gan, Kirby Linvill +3
Measuring similarity between molecules is an important part of virtual screening (VS) experiments deployed during the early stages of drug discovery. Most widely used methods for e…
Small Animal Multivariate Brain Analysis (SAMBA): A High Throughput Pipeline with a Validation Framework
Robert J Anderson, James J Cook, Natalie A Delpratt +6
While many neuroscience questions aim to understand the human brain, much current knowledge has been gained using animal models, which replicate genetic, structural, and connectivi…
A new latent cure rate marker model for survival data
Sungduk Kim, Yingmei Xi, Ming-Hui Chen
To address an important risk classification issue that arises in clinical practice, we propose a new mixture model via latent cure rate markers for survival data with a cure fracti…