23 citations
6 papers
Automated Whole Slide Imaging for Label-Free Histology using Photon Absorption Remote Sensing Microscopy
James E. D. Tweel, Benjamin R. Ecclestone, Marian Boktor +3
The field of histology relies heavily on antiquated tissue processing and staining techniques that limit the efficiency of pathologic diagnoses of cancer and other diseases. Curren…
Time-domain feature extraction for target-specificity in Photoacoustic Remote Sensing Microscopy
Nicholas Pellegrino, Benjamin R. Ecclestone, Paul Fieguth +1
Photoacoustic Remote Sensing (PARS) microscopy is an emerging label-free optical absorption imaging modality. PARS operates by capturing nanosecond-scale optical perturbations gene…
Three-Dimensional Virtual Histology in Unprocessed Resected Tissues with Photoacoustic Remote Sensing (PARS) Microscopy and Optical Coherence Tomography
Benjamin R. Ecclestone, Zohreh Hosseinaee, Nima Abbasi +4
Histological images are critical in the diagnosis and treatment of cancers. Unfortunately, the current method for capturing these microscopy images require resource intensive tissu…
Hyperspectral Absorption Microscopy Using Photoacoustic Remote Sensing
Kevan Bell, Lyazzat Mukhangaliyeva, Layla Khalili +1
An improved method of remote optical absorption spectroscopy and hyperspectral optical absorption imaging is described which takes advantage of the photoacoustic remote sensing det…
Single Acquisition Label-free Histology-like Imaging with Dual Contrast Photoacoustic Remote Sensing Microscopy
Benjamin Ecclestone, Deepak Dinakaran, Parsin Haji Reza
Significance: Histopathological analysis of tissues is an essential tool for grading, staging, diagnosing and resecting cancers and other malignancies. Current histopathological te…
Label-free, non-contact, in-vivo ophthalmic imaging using photoacoustic remote sensing microscopy
Zohreh Hosseinaee, Layla Khalili, James Alex Tummon Simmons +2
We present the first label-free, non-contact, in-vivo imaging of the ocular vasculature using photoacoustic remote sensing (PARS) microscopy. Both anterior and posterior segments m…