7 papers
Virtual Histological Staining of Label-Free Total Absorption Photoacoustic Remote Sensing (TA-PARS)
Marian Boktor, Benjamin Ecclestone, Vlad Pekar +4
Histopathological visualizations are a pillar of modern medicine and biological research. Surgical oncology relies exclusively on post-operative histology to determine definitive s…
Label-free virtual Hematoxylin and Eosin (H&E) staining using second generation Photoacoustic Remote Sensing (PARS)
Benjamin R. Ecclestone, Kevan Bell, Sarah Sparkes +3
In the past decades, absorption modalities have emerged as powerful tools for label-free functional and structural imaging of cells and tissues. Many biomolecules present unique ab…
Three-Dimensional Virtual Histology in Unprocessed Resected Tissues with Photoacoustic Remote Sensing (PARS) Microscopy and Optical Coherence Tomography
Benjamin R. Ecclestone, Zohreh Hosseinaee, Nima Abbasi +4
Histological images are critical in the diagnosis and treatment of cancers. Unfortunately, the current method for capturing these microscopy images require resource intensive tissu…
Single Acquisition Label-free Histology-like Imaging with Dual Contrast Photoacoustic Remote Sensing Microscopy
Benjamin Ecclestone, Deepak Dinakaran, Parsin Haji Reza
Significance: Histopathological analysis of tissues is an essential tool for grading, staging, diagnosing and resecting cancers and other malignancies. Current histopathological te…
Improving Maximal Safe Brain Tumor Resection with Photoacoustic Remote Sensing Microscopy
Benjamin R. Ecclestone, Kevan Bell, Saad Abbasi +5
Malignant brain tumors are among the deadliest neoplasms with the lowest survival rates of any cancer type. In considering surgical tumor resection, suboptimal extent of resection…
Reflection-mode virtual histology using photoacoustic remote sensing microscopy
Kevan Bell, Saad Abbasi, Deepak Dinakaran +5
Histological visualizations are critical to clinical disease management and are fundamental to biological understanding. However, current approaches that rely on bright-field micro…