6 papers · 1 filter
Automated Whole Slide Imaging for Label-Free Histology using Photon Absorption Remote Sensing Microscopy
James E. D. Tweel, Benjamin R. Ecclestone, Marian Boktor +3
The field of histology relies heavily on antiquated tissue processing and staining techniques that limit the efficiency of pathologic diagnoses of cancer and other diseases. Curren…
Label-free virtual Hematoxylin and Eosin (H&E) staining using second generation Photoacoustic Remote Sensing (PARS)
Benjamin R. Ecclestone, Kevan Bell, Sarah Sparkes +3
In the past decades, absorption modalities have emerged as powerful tools for label-free functional and structural imaging of cells and tissues. Many biomolecules present unique ab…
Three-Dimensional Virtual Histology in Unprocessed Resected Tissues with Photoacoustic Remote Sensing (PARS) Microscopy and Optical Coherence Tomography
Benjamin R. Ecclestone, Zohreh Hosseinaee, Nima Abbasi +4
Histological images are critical in the diagnosis and treatment of cancers. Unfortunately, the current method for capturing these microscopy images require resource intensive tissu…
Single Acquisition Label-free Histology-like Imaging with Dual Contrast Photoacoustic Remote Sensing Microscopy
Benjamin Ecclestone, Deepak Dinakaran, Parsin Haji Reza
Significance: Histopathological analysis of tissues is an essential tool for grading, staging, diagnosing and resecting cancers and other malignancies. Current histopathological te…
Reflection-mode virtual histology using photoacoustic remote sensing microscopy
Kevan Bell, Saad Abbasi, Deepak Dinakaran +5
Histological visualizations are critical to clinical disease management and are fundamental to biological understanding. However, current approaches that rely on bright-field micro…
Histopathology for Mohs Micrographic Surgery with Photoacoustic Remote Sensing Microscopy
Benjamin R. Ecclestone, Kevan Bell, Saad Abbasi +4
Mohs micrographic surgery (MMS) is a precise oncological technique where layers of tissue are resected and examined with intraoperative histopathology to minimize the removal of no…