13 citations · 38 across the 12 of their papers we have counts for
12 papers
Pathology-Guided Virtual Staining Metric for Evaluation and Training
Qiankai Wang, James E. D. Tweel, Parsin Haji Reza +1
Virtual staining has emerged as a powerful alternative to traditional histopathological staining techniques, enabling rapid, reagent-free image transformations. However, existing e…
Photon Absorption Remote Sensing Virtual Histopathology: A Preliminary Exploration of Diagnostic Equivalence to Gold-Standard H&E Staining in Skin Cancer Excisional Biopsies
Benjamin R. Ecclestone, James E. D. Tweel, Marie Abi Daoud +7
Photon Absorption Remote Sensing (PARS) enables label-free imaging of subcellular morphology by observing biomolecule specific absorption interactions. Coupled with deep-learning,…
Investigation of Non-Radiative Relaxation Dynamics Under Pulsed Excitation Using Photon Absorption Remote Sensing: A Proof-of-Principle Study in Mechanical Sensing
Channprit Kaur, Aria Hajiahmadi, Benjamin R. Ecclestone +3
The mechanical properties of micro-scale bio-entities are fundamental for understanding their functions and pathological states. However, current methods for assessing elastic prop…
Photon Absorption Remote Sensing (PARS): A Comprehensive Approach to Label-free Absorption Microscopy Across Biological Scales
Benjamin R. Ecclestone, James A. Tummon Simmons, James E. D. Tweel +3
Label-free optical absorption microscopy techniques have evolved as effective tools for non-invasive chemical specific structural, and functional imaging. Yet most modern label-fre…
Label-Free Non-Contact Structural and Functional Vascular Imaging using Photon Absorption Remote Sensing
James A. Tummon Simmons, Sarah J. Werezak, Benjamin R. Ecclestone +3
Vascular imaging is critical for understanding human health and disease. Most established non-contact and label-free optical techniques capture predominantly structural information…
Virtual Histology with Photon Absorption Remote Sensing using a Cycle-Consistent Generative Adversarial Network with Weakly Registered Pairs
James E. D. Tweel, Benjamin R. Ecclestone, Marian Boktor +3
Modern histopathology relies on the microscopic examination of thin tissue sections stained with histochemical techniques, typically using brightfield or fluorescence microscopy. H…
Automated Whole Slide Imaging for Label-Free Histology using Photon Absorption Remote Sensing Microscopy
James E. D. Tweel, Benjamin R. Ecclestone, Marian Boktor +3
The field of histology relies heavily on antiquated tissue processing and staining techniques that limit the efficiency of pathologic diagnoses of cancer and other diseases. Curren…
K-Means for Noise-Insensitive Multi-Dimensional Feature Learning
Nicholas Pellegrino, Paul Fieguth, Parsin Haji Reza
Many measurement modalities which perform imaging by probing an object pixel-by-pixel, such as via Photoacoustic Microscopy, produce a multi-dimensional feature (typically a time-d…
Label-free virtual Hematoxylin and Eosin (H&E) staining using second generation Photoacoustic Remote Sensing (PARS)
Benjamin R. Ecclestone, Kevan Bell, Sarah Sparkes +3
In the past decades, absorption modalities have emerged as powerful tools for label-free functional and structural imaging of cells and tissues. Many biomolecules present unique ab…
In vivo functional and structural retina imaging using multimodal photoacoustic remote sensing microscopy and optical coherence tomography
Zohreh Hosseinaee, Nicholas Pellegrino, Nima Abbasi +4
We have developed a multimodal photoacoustic remote sensing (PARS) microscope combined with swept source optical coherence tomography for in vivo, non-contact retinal imaging. Buil…
Single Acquisition Label-free Histology-like Imaging with Dual Contrast Photoacoustic Remote Sensing Microscopy
Benjamin Ecclestone, Deepak Dinakaran, Parsin Haji Reza
Significance: Histopathological analysis of tissues is an essential tool for grading, staging, diagnosing and resecting cancers and other malignancies. Current histopathological te…
Non-contact, in-vivo, functional, and structural ophthalmic imaging using multimodal photoacoustic remote sensing (PARS) microscopy and optical coherence tomography (OCT)
Zohreh Hosseinaee, Nima Abbasi, Layla Khali +3
Early diagnosis of ocular diseases improves the understanding of pathophysiology and helps with accurate monitoring and effective treatment. Advanced multimodal ocular imaging plat…