8 papers
Photon Absorption Remote Sensing (PARS): Comprehensive Absorption Imaging Enabling Label-Free Biomolecule Characterization and Mapping
Benjamin R. Ecclestone, James A. Tummon Simmons, James E. D. Tweel +2
Label-free optical absorption microscopy techniques continue to evolve as promising tools for label-free histopathological imaging of cells and tissues. However, critical challenge…
Virtual Histological Staining of Label-Free Total Absorption Photoacoustic Remote Sensing (TA-PARS)
Marian Boktor, Benjamin Ecclestone, Vlad Pekar +4
Histopathological visualizations are a pillar of modern medicine and biological research. Surgical oncology relies exclusively on post-operative histology to determine definitive s…
Three-Dimensional Virtual Histology in Unprocessed Resected Tissues with Photoacoustic Remote Sensing (PARS) Microscopy and Optical Coherence Tomography
Benjamin R. Ecclestone, Zohreh Hosseinaee, Nima Abbasi +4
Histological images are critical in the diagnosis and treatment of cancers. Unfortunately, the current method for capturing these microscopy images require resource intensive tissu…
Hyperspectral Absorption Microscopy Using Photoacoustic Remote Sensing
Kevan Bell, Lyazzat Mukhangaliyeva, Layla Khalili +1
An improved method of remote optical absorption spectroscopy and hyperspectral optical absorption imaging is described which takes advantage of the photoacoustic remote sensing det…
Improving Maximal Safe Brain Tumor Resection with Photoacoustic Remote Sensing Microscopy
Benjamin R. Ecclestone, Kevan Bell, Saad Abbasi +5
Malignant brain tumors are among the deadliest neoplasms with the lowest survival rates of any cancer type. In considering surgical tumor resection, suboptimal extent of resection…
Reflection-mode virtual histology using photoacoustic remote sensing microscopy
Kevan Bell, Saad Abbasi, Deepak Dinakaran +5
Histological visualizations are critical to clinical disease management and are fundamental to biological understanding. However, current approaches that rely on bright-field micro…