13 citations · 26 across the 9 of their papers we have counts for
10 papers
Label-Free Whole Slide Virtual Multi-Staining Using Dual-Excitation Photon Absorption Remote Sensing Microscopy
James E. D. Tweel, Benjamin R. Ecclestone, James A. Tummon Simmons +1
Histochemical staining is essential for visualizing tissue architecture and cellular morphology but is destructive and limited by the availability of tissue for multiple stains. Vi…
Pathology-Guided Virtual Staining Metric for Evaluation and Training
Qiankai Wang, James E. D. Tweel, Parsin Haji Reza +1
Virtual staining has emerged as a powerful alternative to traditional histopathological staining techniques, enabling rapid, reagent-free image transformations. However, existing e…
Photon Absorption Remote Sensing (PARS): Comprehensive Absorption Imaging Enabling Label-Free Biomolecule Characterization and Mapping
Benjamin R. Ecclestone, James A. Tummon Simmons, James E. D. Tweel +2
Label-free optical absorption microscopy techniques continue to evolve as promising tools for label-free histopathological imaging of cells and tissues. However, critical challenge…
Photon Absorption Remote Sensing Virtual Histopathology: A Preliminary Exploration of Diagnostic Equivalence to Gold-Standard H&E Staining in Skin Cancer Excisional Biopsies
Benjamin R. Ecclestone, James E. D. Tweel, Marie Abi Daoud +7
Photon Absorption Remote Sensing (PARS) enables label-free imaging of subcellular morphology by observing biomolecule specific absorption interactions. Coupled with deep-learning,…
Investigation of Non-Radiative Relaxation Dynamics Under Pulsed Excitation Using Photon Absorption Remote Sensing: A Proof-of-Principle Study in Mechanical Sensing
Channprit Kaur, Aria Hajiahmadi, Benjamin R. Ecclestone +3
The mechanical properties of micro-scale bio-entities are fundamental for understanding their functions and pathological states. However, current methods for assessing elastic prop…
Photon Absorption Remote Sensing (PARS): A Comprehensive Approach to Label-free Absorption Microscopy Across Biological Scales
Benjamin R. Ecclestone, James A. Tummon Simmons, James E. D. Tweel +3
Label-free optical absorption microscopy techniques have evolved as effective tools for non-invasive chemical specific structural, and functional imaging. Yet most modern label-fre…
Label-Free Non-Contact Structural and Functional Vascular Imaging using Photon Absorption Remote Sensing
James A. Tummon Simmons, Sarah J. Werezak, Benjamin R. Ecclestone +3
Vascular imaging is critical for understanding human health and disease. Most established non-contact and label-free optical techniques capture predominantly structural information…
Multi-Channel Feature Extraction for Virtual Histological Staining of Photon Absorption Remote Sensing Images
Marian Boktor, James E. D. Tweel, Benjamin R. Ecclestone +3
Accurate and fast histological staining is crucial in histopathology, impacting diagnostic precision and reliability. Traditional staining methods are time-consuming and subjective…
Virtual Histology with Photon Absorption Remote Sensing using a Cycle-Consistent Generative Adversarial Network with Weakly Registered Pairs
James E. D. Tweel, Benjamin R. Ecclestone, Marian Boktor +3
Modern histopathology relies on the microscopic examination of thin tissue sections stained with histochemical techniques, typically using brightfield or fluorescence microscopy. H…
Automated Whole Slide Imaging for Label-Free Histology using Photon Absorption Remote Sensing Microscopy
James E. D. Tweel, Benjamin R. Ecclestone, Marian Boktor +3
The field of histology relies heavily on antiquated tissue processing and staining techniques that limit the efficiency of pathologic diagnoses of cancer and other diseases. Curren…