372 citations
- National Institutes of HealthUS14 papers
- Yale UniversityUS5 papers
- National Institutes of Health Clinical CenterUS4 papers
- National University of SingaporeSG3 papers
- Oregon Health & Science UniversityUS3 papers
- The University of Texas Health Science Center at HoustonUS3 papers
- University of California San DiegoUS3 papers
- Carnegie Mellon UniversityUS2 papers
- Cornell UniversityUS2 papers
- Harvard UniversityUS2 papers
- Imperial College LondonGB2 papers
- National Eye InstituteUS2 papers
20 papers
Fold-switching proteins push the boundaries of conformational ensemble prediction
Myeongsang Lee, Lauren L. Porter
A protein's function depends critically on its conformational ensemble, a collection of energy weighted structures whose balance depends on temperature and environment. Though rece…
Repurposing Annotation Guidelines to Instruct LLM Annotators: A Case Study
Kon Woo Kim, Rezarta Islamaj, Jin-Dong Kim +2
This study investigates how existing annotation guidelines can be repurposed to instruct large language model (LLM) annotators for text annotation tasks. Traditional guidelines are…
LMOD+: A Comprehensive Multimodal Dataset and Benchmark for Developing and Evaluating Multimodal Large Language Models in Ophthalmology
Zhenyue Qin, Yang Liu, Yu Yin +13
Vision-threatening eye diseases pose a major global health burden, with timely diagnosis limited by workforce shortages and restricted access to specialized care. While multimodal…
Memorization in Large Language Models in Medicine: Prevalence, Characteristics, and Implications
Anran Li, Lingfei Qian, Mengmeng Du +18
Large Language Models (LLMs) have demonstrated significant potential in medicine, with many studies adapting them through continued pre-training or fine-tuning on medical data to e…
Environment Scan of Generative AI Infrastructure for Clinical and Translational Science
Betina Idnay, Zihan Xu, William G. Adams +54
This study reports a comprehensive environmental scan of the generative AI (GenAI) infrastructure in the national network for clinical and translational science across 36 instituti…
AI Workflow, External Validation, and Development in Eye Disease Diagnosis
Qingyu Chen, Tiarnan D L Keenan, Elvira Agron +35
Timely disease diagnosis is challenging due to increasing disease burdens and limited clinician availability. AI shows promise in diagnosis accuracy but faces real-world applicatio…