193 citations · 845 across the 19 of their papers we have counts for
20 papers
Roadmap for Condensates in Cell Biology
Dilimulati Aierken, Sebastian Aland, Stefano Bo +38
Biomolecular condensates govern essential cellular processes yet elude description by traditional equilibrium models. This roadmap, distilled from structured discussions at a works…
Polydisperse polymer fractionation between phases
J. Pedro de Souza, William M. Jacobs, Howard A. Stone
Polymer mixtures fractionate between phases depending on their molecular weight. Consequently, by varying solvent conditions, a polydisperse polymer sample can be separated between…
Nonequilibrium interfacial properties of chemically driven fluids
Yongick Cho, William M. Jacobs
Chemically driven fluids can demix to form condensed droplets that exhibit phase behaviors not observed at equilibrium. In particular, nonequilibrium interfacial properties can eme…
Interplay between self-assembly and phase separation in a polymer-complex model
Tianhao Li, W. Benjamin Rogers, William M. Jacobs
We present a theoretical model for predicting the phase behavior of polymer solutions in which phase separation competes with oligomerization. Specifically, we consider scenarios i…
Active learning of the thermodynamics-dynamics tradeoff in protein condensates
Yaxin An, Michael A. Webb, William M. Jacobs
Phase-separated biomolecular condensates exhibit a wide range of dynamical properties, which depend on the sequences of the constituent proteins and RNAs. However, it is unclear to…
Theory and simulation of multiphase coexistence in biomolecular mixtures
William M. Jacobs
Biomolecular condensates constitute a newly recognized form of spatial organization in living cells. Although many condensates are believed to form as a result of phase separation,…