811 citations · 6.8k across the 93 of their papers we have counts for
10 papers · 1 filter
Diversity of immune strategies explained by adaptation to pathogen statistics
Andreas Mayer, Thierry Mora, Olivier Rivoire +1
Biological organisms have evolved a wide range of immune mechanisms to defend themselves against pathogens. Beyond molecular details, these mechanisms differ in how protection is a…
Local equilibrium in bird flocks
Thierry Mora, Aleksandra M. Walczak, Lorenzo Del Castello +6
The correlated motion of flocks is an instance of global order emerging from local interactions. An essential difference with analogous ferromagnetic systems is that flocks are act…
repgenHMM: a dynamic programming tool to infer the rules of immune receptor generation from sequence data
Yuval Elhanati, Quentin Marcou, Thierry Mora +1
The diversity of the immune repertoire is initially generated by random rearrangements of the receptor gene during early T and B cell development. Rearrangement scenarios are compo…
Habitat Fluctuations Drive Species Covariation in the Human Microbiota
Charles K. Fisher, Thierry Mora, Aleksandra M. Walczak
Two species with similar resource requirements respond in a characteristic way to variations in their habitat -- their abundances rise and fall in concert. We use this idea to lear…
Noise expands the response range of the Bacillus subtilis competence circuit
Andrew Mugler, Mark Kittisopikul, Luke Hayden +4
Gene regulatory circuits must contend with intrinsic noise that arises due to finite numbers of proteins. While some circuits act to reduce this noise, others appear to exploit it.…
Extending the dynamic range of transcription factor action by translational regulation
Thomas R. Sokolowski, Aleksandra M. Walczak, William Bialek +1
A crucial step in the regulation of gene expression is binding of transcription factor (TF) proteins to regulatory sites along the DNA. But transcription factors act at nanomolar c…