811 citations · 6.8k across the 93 of their papers we have counts for
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The Structure of Genealogies in the Presence of Purifying Selection: A "Fitness-Class Coalescent"
Aleksandra M. Walczak, Lauren E. Nicolaisen, Joshua B. Plotkin +1
Compared to a neutral model, purifying selection distorts the structure of genealogies and hence alters the patterns of sampled genetic variation. Although these distortions may be…
The structure of allelic diversity in the presence of purifying selection
Michael M. Desai, Lauren E. Nicolaisen, Aleksandra M. Walczak +1
In the absence of selection, the structure of allelic diversity is described by the elegant sampling formula of Ewens. This formula has helped shape our expectations of empirical p…
Analytic methods for modeling stochastic regulatory networks
Aleksandra M. Walczak, Andrew Mugler, Chris H. WIggins
The past decade has seen a revived interest in the unavoidable or intrinsic noise in biochemical and genetic networks arising from the finite copy number of the participating speci…
Telling time with an intrinsically noisy clock
Andrew Mugler, Aleksandra M. Walczak, Chris H. Wiggins
Intracellular transmission of information via chemical and transcriptional networks is thwarted by a physical limitation: the finite copy number of the constituent chemical species…