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50 papers
Persistence-Speed Coupling Enhances the Search Efficiency of Migrating Immune Cells
M. Reza Shaebani, Robin Jose, Ludger Santen +2
Migration of immune cells within the human body allows them to fulfill their main function of detecting pathogens. Adopting an optimal navigation and search strategy by these cells…
Self-organized lane-formation in bidirectional transport of molecular motors
Robin Jose, Ludger Santen
Within cells, vesicles and proteins are actively transported several micrometers along the cytoskeletal filaments. The transport along microtubules is propelled by dynein and kines…
Cell-Type-Specific Differences in KDEL Receptor Clustering in Mammalian Cells
Achim Bauer, Ludger Santen, Manfred J. Schmitt +2
In eukaryotic cells, KDEL receptors (KDELRs) facilitate the retrieval of endoplasmic reticulum (ER) luminal proteins from the Golgi compartment back to the ER. Apart from the well-…
Bidirectional Non-Markovian Exclusion Processes
Robin Jose, Chikashi Arita, Ludger Santen
Bidirectional transport in (quasi) one-dimensional systems generically leads to cluster-formation and small particle currents. This kind of transport can be described by the asymme…
Trapping in and escape from branched structures of neuronal dendrites
Robin Jose, Ludger Santen, M. Reza Shaebani
We present a coarse-grained model for stochastic transport of noninteracting chemical signals inside neuronal dendrites and show how first-passage properties depend on the key stru…
Unraveling the structure of treelike networks from first-passage times of lazy random walkers
M. Reza Shaebani, Robin Jose, Christian Sand +1
We study the problem of random search in finite networks with a tree topology, where it is expected that the distribution of the first-passage time F(t) decays exponentially. We sh…