5 citations · 5 across the 4 of their papers we have counts for
13 papers
A new lipid-structured model to investigate the opposing effects of LDL and HDL on atherosclerotic plaque macrophages
Keith L Chambers, Mary R Myerscough, Helen M Byrne
Atherosclerotic plaques form in artery walls due to a chronic inflammatory response driven by lipid accumulation. A key component of the inflammatory response is the interaction be…
A method to coarse-grain multi-agent stochastic systems with regions of multistability
Daria Stepanova, Helen M. Byrne, Philip K. Maini +1
Hybrid multiscale modelling has emerged as a useful framework for modelling complex biological phenomena. However, when accounting for stochasticity in the internal dynamics of age…
Phenotypic variation modulates the growth dynamics and response to radiotherapy of solid tumours under normoxia and hypoxia
Giulia L. Celora, Helen M. Byrne, Christos Zois +1
In cancer, treatment failure and disease recurrence have been associated with small subpopulations of cancer cells with a stem-like phenotype. In this paper, we develop and investi…
Topological data analysis distinguishes parameter regimes in the Anderson-Chaplain model of angiogenesis
John T. Nardini, Bernadette J. Stolz, Kevin B. Flores +2
Angiogenesis is the process by which blood vessels form from pre-existing vessels. It plays a key role in many biological processes, including embryonic development and wound heali…
A shell model of eye growth and elasticity
L. S. Kimpton, B. J. Walker, C. L. Hall +4
The eye grows during childhood to position the retina at the correct distance behind the lens to enable focused vision, a process called emmetropization. Animal studies have demons…
Asymptotic Analysis of a Two-Phase Model of Solid Tumour Growth
Andrea Genovese de Oliveira, John R. King
We investigate avascular tumour growth as a two-phase process consisting of cells and liquid. Based on the one-dimensional continuum moving-boundary model formulated by (Byrne, Kin…