184 citations · 704 across the 38 of their papers we have counts for
3 papers · 1 filter
3D hybrid modeling of vascular network formation
Holger Perfahl, Barry D Hughes, Tomas Alaracon +4
We develop an agent-based model of vasculogenesis, the de novo formation of blood vessels. Endothelial cells in the vessel network are viewed as linearly elastic spheres and are of…
The Role of the Hes1 Crosstalk Hub in Notch-Wnt Interactions of the Intestinal Crypt
Sophie K. Kay, Heather A. Harrington, Sarah Shepherd +5
The Notch pathway plays a vital role in determining whether cells in the intestinal epithelium adopt a secretory or an absorptive phenotype. Cell fate specification is coordinated…
Decomposing the parameter space of biological networks via a numerical discriminant approach
Heather A. Harrington, Dhagash Mehta, Helen M. Byrne +1
Many systems in biology, physics and engineering can be described by systems of ordinary differential equation containing many parameters. When studying the dynamic behavior of the…