184 citations · 704 across the 38 of their papers we have counts for
4 papers · 1 filter
Identifying and characterising the impact of excitability in a mathematical model of tumour-immune interactions
Ana Osojnik, Eamonn A. Gaffney, Michael Davies +2
We study a five-compartment mathematical model originally proposed by Kuznetsov et al. (1994) to investigate the effect of nonlinear interactions between tumour and immune cells in…
A Multiphase Model of Growth Factor-Regulated Atherosclerotic Cap Formation
Michael G. Watson, Helen M. Byrne, Charlie Macaskill +1
Atherosclerosis is characterised by the growth of fatty plaques in the inner (intimal) layer of the artery wall. In mature plaques, vascular smooth muscle cells (SMCs) are recruite…
Topological Methods for Characterising Spatial Networks: A Case Study in Tumour Vasculature
Helen M Byrne, Heather A Harrington, Ruth Muschel +3
Understanding how the spatial structure of blood vessel networks relates to their function in healthy and abnormal biological tissues could improve diagnosis and treatment for dise…
Evolutionary dynamics of competing phenotype-structured populations in periodically fluctuating environments
Aleksandra Ardaševa, Robert A. Gatenby, Alexander R. A. Anderson +3
Living species, ranging from bacteria to animals, exist in environmental conditions that exhibit spatial and temporal heterogeneity which requires them to adapt. Risk-spreading thr…