184 citations · 704 across the 38 of their papers we have counts for
3 papers · 1 filter
Hybrid approaches for multiple-species stochastic reaction-diffusion models
Fabian Spill, Pilar Guerrero, Tomas Alarcon +2
Reaction-diffusion models are used to describe systems in fields as diverse as physics, chemistry, ecology and biology. The fundamental quantities in such models are individual ent…
Models, measurement and inference in epithelial tissue dynamics
O. J. Maclaren, A. G. Fletcher, H. M. Byrne +1
The majority of solid tumours arise in epithelia and therefore much research effort has gone into investigating the growth, renewal and regulation of these tissues. Here we review…
Mathematical and Statistical Techniques for Systems Medicine: The Wnt Signaling Pathway as a Case Study
Adam L. MacLean, Heather A. Harrington, Michael P. H. Stumpf +1
The last decade has seen an explosion in models that describe phenomena in systems medicine. Such models are especially useful for studying signaling pathways, such as the Wnt path…