DNA looping: the consequences and its control
arXiv:q-bio/0609045 · doi:10.1016/j.sbi.2006.05.008
Abstract
The formation of DNA loops by proteins and protein complexes is ubiquitous to many fundamental cellular processes, including transcription, recombination, and replication. Here we review recent advances in understanding the properties of DNA looping in its natural context and how they propagate to the cellular behavior through gene regulation. The results of connecting the molecular properties with cellular physiology indicate that looping of DNA in vivo is much more complex and easier than predicted from current models and reveals a wealth of previously unappreciated details.
References in corpus (4)
Cited by in corpus (9)
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- Concentration and Length Dependence of DNA Looping in Transcriptional Regulation
- Accurate prediction of gene expression by integration of DNA sequence statistics with detailed modeling of transcription regulation
- Control of gene expression by modulated self-assembly
- Facilitation of DNA loop formation by protein-DNA non-specific interactions
- Mathematical model of alternative mechanism of telomere length maintenance
- Transcription and the Pitch Angle of DNA
- Efficiency and versatility of distal multisite transcription regulation
- Colloidal particle motion as a diagnostic of DNA conformational transitions