150 citations
2 papers
q-bio.MN2005★ 150 cited
Signal processing in the TGF-beta superfamily ligand-receptor network
Jose M. G. Vilar, Ronald Jansen, Chris Sander
The TGF-beta pathway plays a central role in tissue homeostasis and morphogenesis. It transduces a variety of extracellular signals into intracellular transcriptional responses tha…
q-bio.MN2005★ 150 cited
DNA looping in gene regulation: from the assembly of macromolecular complexes to the control of transcriptional noise
Jose M. G. Vilar, Leonor Saiz
The formation of DNA loops by proteins and protein complexes that bind at distal DNA sites plays a central role in many cellular processes, such as transcription, recombination, an…