Colloidal particle motion as a diagnostic of DNA conformational transitions
arXiv:0710.1048
Abstract
Tethered particle motion is an experimental technique to monitor conformational changes in single molecules of DNA in real time, by observing the position fluctuations of a micrometer-size particle attached to the DNA. This article reviews some recent work on theoretical problems inherent in the interpretation of TPM experiments, both in equilibrium and dynamical aspects.
19pp. Accepted for publication in Curr Op Colloid Interf Science
References in corpus (8)
- Exact theory of kinkable elastic polymers
- Excluded-Volume Effects in Tethered-Particle Experiments: Bead Size Matters
- A generalized theory of semiflexible polymers
- DNA looping: the consequences and its control
- Inferring the in vivo looping properties of DNA
- DNA Looping Kinetics Analyzed Using Diffusive Hidden Markov Model
- Protein-Mediated DNA Loops: Effects of Protein Bridge Size and Kinks
- Elementary simulation of tethered Brownian motion