Choroidal vasculature imaging with laser Doppler holography

Abstract

The choroid is a highly vascularized tissues supplying the retinal pigment epithelium and photoreceptors. Its implication in retinal diseases is gaining increasing interest. However, investigating the anatomy and flow of the choroid remains challenging. Here we show that laser Doppler holography provides high contrast imaging of choroidal vessels in humans, with a spatial resolution comparable to state of the art indocyanine green angiography and optical coherence tomography. Additionally, laser Doppler holography contributes to sort out choroidal arteries and veins by using a power Doppler spectral analysis. We thus demonstrate the potential of laser Doppler holography to improve our understanding of the anatomy and flow of the choroidal vascular network.

References in corpus (3)

• In vivo laser Doppler holography of the human retina
• Holographic laser Doppler imaging of microvascular blood flow
• High speed optical holography of retinal blood flow

Cited by in corpus (5)

• Waveform analysis of human retinal and choroidal blood flow with laser Doppler holography
• Reverse contrast laser Doppler holography for lower frame rate retinal and choroidal blood flow imaging
• Laser Doppler holography of the anterior segment for blood flow imaging, eye tracking, and transparency assessment
• Measuring choriocapillaris blood flow with laser Doppler optical coherence tomography
• Analysis of retinal and choroidal images measured by laser Doppler holography