activity
20152026
most citedIn vivo laser Doppler holography of the human retina

51 citations · 136 across the 15 of their papers we have counts for

collaborators

17 papers

physics.optics2026

High-resolution retinal matrix imaging via computational motion and aberration correction

Aymeric Melt, Léo Puyo, Victor Barolle +3

High-resolution optical imaging of the human retina is essential for diagnosing ophthalmic and neurodegenerative diseases. While adaptive optics combined with coherence gating can…

physics.optics2026

Spatially or temporally resolved phase-based optoretinography with actively-tracked point-scanning optical coherence tomography

Léo Puyo, Jonas Franke, Felix Zeisberger +2

Optoretinography is a promising approach to measure visual function but its clinical translation has remained confined to research settings due to demanding hardware requirements.…

physics.optics2025★ 3 cited

Measuring choriocapillaris blood flow with laser Doppler optical coherence tomography

Léo Puyo, Jonas Franke, Lisa Kutzner +3

We report on using a laser Doppler processing of Fourier-domain optical coherence tomography (OCT) data for the assessment of pulsatile blood flow in the choriocapillaris. Signal f…

physics.optics2023

Diffuse-illumination holographic optical coherence tomography

Léo Puyo, Clara Pfäffle, Hendrik Spahr +4

Holographic optical coherence tomography (OCT) is a powerful imaging technique, but its ability to reveal low-reflectivity features is limited. In this study, we performed holograp…

stat.AP2021★ 2 cited

Real-Time Estimation of COVID-19 Infections: Deconvolution and Sensor Fusion

Maria Jahja, Andrew Chin, Ryan J. Tibshirani

We propose, implement, and evaluate a method to estimate the daily number of new symptomatic COVID-19 infections, at the level of individual U.S. counties, by deconvolving daily re…

physics.med-ph2021★ 4 cited

Laser Doppler holography of the anterior segment for blood flow imaging, eye tracking, and transparency assessment

Léo Puyo, Clémentine David, Rana Saad +6

Laser Doppler holography (LDH) is a full-field blood flow imaging technique able to reveal human retinal and choroidal blood flow with high temporal resolution. We here report on u…

physics.med-ph2021★ 25 cited

Waveform analysis of human retinal and choroidal blood flow with laser Doppler holography

Léo Puyo, Michel Paques, Mathias Fink +2

Laser Doppler holography was introduced as a full-field imaging technique to measure blood flow in the retina and choroid with an as yet unrivaled temporal resolution. We here inve…

physics.med-ph2021★ 39 cited

Choroidal vasculature imaging with laser Doppler holography

Léo Puyo, Michel Paques, Mathias Fink +2

The choroid is a highly vascularized tissues supplying the retinal pigment epithelium and photoreceptors. Its implication in retinal diseases is gaining increasing interest. Howeve…

physics.med-ph2020

Retinal blood flow reversal quantitatively monitored in out-of-plane vessels with laser Doppler holography

Léo Puyo, Michel Paques, Michael Atlan

Laser Doppler holography is a planar blood flow imaging technique recently introduced in ophthalmology to image human retinal and choroidal blood flow non-invasively. Here we prese…

physics.med-ph2020★ 2 cited

Real-time digital holography of the retina by principal component analysis

Leo Puyo, Loic Bellonnet-Mottet, Antoine Martin +3

We demonstrate the feasibility of high-quality digital holography of the human retina in real-time with a fast camera and commodity computer hardware. High throughput rendering of…

eess.IV2020★ 7 cited

Reverse contrast laser Doppler holography for lower frame rate retinal and choroidal blood flow imaging

Leo Puyo, Michel Paques, Michael Atlan

Laser Doppler holography (LDH) is an interferometric blood flow imaging technique based on full-field measurements of the Doppler spectrum. LDH has so far been demonstrated in the…

physics.optics2020

Swept-source optical coherence tomography by off-axis Fresnel transform digital holography with an output throughput of 10 Giga voxels per second in real-time

E. Charpentier, F. Lapeyre, J. Gautier +6

We demonstrate swept-source optical coherence tomography in real-time by high throughput digital Fresnel hologram rendering from optically-acquired interferograms with a high-speed…

eess.IV2020

Spatio-temporal filtering in laser Doppler holography for retinal blood flow imaging

Leo Puyo, Michel Paques, Michael Atlan

Laser Doppler holography (LDH) is a full-field interferometric imaging technique recently applied in ophthalmology to measure blood flow, a parameter of high clinical interest. Fro…

physics.med-ph2019

Analysis of retinal and choroidal images measured by laser Doppler holography

L. Puyo, M. Paques, M. Fink +2

Laser Doppler holography (LDH) is a full-field imaging technique that was recently used in the human eye to reveal blood flow contrasts in the retinal and choroidal vasculature non…

physics.optics2018★ 3 cited

Off-axis digital holography with multiplexed volume Bragg gratings

Leo Puyo, Jean-Pierre Huignard, Michael Atlan

We report on an optical imaging design based on common-path off-axis digital holography, using a multiplexed volume Bragg grating. In the reported method, a reference optical wave…

physics.med-ph2018★ 51 cited

In vivo laser Doppler holography of the human retina

L. Puyo, M. Paques, M. Fink +2

The eye offers a unique opportunity for non-invasive exploration of cardiovascular diseases. Optical angiography in the retina requires sensitive measurements, which hinders conven…

physics.med-ph2015

Pulsatile microvascular blood flow imaging by short-time Fourier transform analysis of ultrafast laser holographic interferometry

L. Puyo, I. Ferezou, A. Rancillac +5

We report on wide-field imaging of pulsatile microvascular blood flow in the exposed cerebral cortex of a mouse by holographic interferometry. We recorded interferograms of laser l…