Discovery in space of ethanolamine, the simplest phospholipid head group

Abstract

Cell membranes are a key element of life because they keep the genetic material and metabolic machinery together. All present cell membranes are made of phospholipids, yet the nature of the first membranes and the origin of phospholipids are still under debate. We report here the first detection in space of ethanolamine, NH${}_2$CH${}_2$CH${}_2$OH, which forms the hydrophilic head of the simplest and second most abundant phospholipid in membranes. The molecular column density of ethanolamine in interstellar space is $N$=(1.51$\pm$0.07)$\times$10${}^{13}$ cm${}^{-2}$, implying a molecular abundance with respect to H${}_2$ of (0.9-1.4)$\times$10${}^{-10}$. Previous studies reported its presence in meteoritic material but they suggested that it is synthesized in the meteorite itself by decomposition of amino acids. However, we find that the proportion of the molecule with respect to water in the interstellar medium is similar to the one found in the meteorite (10${}^{-6}$). These results indicate that ethanolamine forms efficiently in space and, if delivered onto early Earth, it could have contributed to the assembling and early evolution of primitive membranes.

Accepted in PNAS (Proceedings of the National Academy of Sciences of the United States of America)

References in corpus (15)

• Complex Chemistry in Star-Forming Regions: An Expanded Gas-Grain Warm-up Chemical Model
• Formation of methyl formate and other organic species in the warm-up phase of hot molecular cores
• 2021 Census of Interstellar, Circumstellar, Extragalactic, Protoplanetary Disk, and Exoplanetary Molecules
• The largest oxigen bearing organic molecule repository
• Experimental evidence for Glycolaldehyde and Ethylene Glycol formation by surface hydrogenation of CO molecules under dense molecular cloud conditions
• Modeling Complex Organic Molecules in dense regions: Eley-Rideal and complex induced reaction
• Tracing shocks and photodissociation in the Galactic center region
• Yebes 40 m radio telescope and the broad band NANOCOSMOS receivers at 7 mm and 3 mm for line surveys
• A non-energetic mechanism for glycine formation in the interstellar medium
• Organic Molecules in the Galactic Center. Hot Core Chemistry without Hot Cores
• Prebiotic precursors of the primordial RNA world in space: Detection of NH${}_2$OH
• Discovery of interstellar ketenyl (HCCO), a surprisingly abundant radical
• Cloud-cloud collision as drivers of the chemical complexity in Galactic Centre molecular clouds
• First detection of the pre-biotic molecule glycolonitrile (HOCH2CN) in the interstellar medium
• Propargylimine in the laboratory and in space: millimetre-wave spectroscopy and first detection in the ISM

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