Solution nuclear magnetic resonance spectroscopy on a nanostructured diamond chip
arXiv:1701.01401 · doi:10.1038/s41467-017-00266-4
Abstract
We demonstrate nuclear magnetic resonance (NMR) spectroscopy of picoliter-volume solutions with a nanostructured diamond chip. Using optical interferometric lithography, diamond surfaces were nanostructured with dense, high-aspect-ratio nanogratings, enhancing the surface area by more than a factor of 15 over mm^2 regions of the chip. The nanograting sidewalls were doped with nitrogen-vacancy (NV) centers so that more than 10 million NV centers in a (25 micrometer)^2 laser spot are located close enough to the diamond surface (5 nm) to detect the NMR spectrum of 1 pL of fluid lying within adjacent nanograting grooves. The platform was used to perform 1H and 19F NMR spectroscopy at room temperature in magnetic fields below 50 mT. Using a solution of CsF in glycerol, we demonstrate that 4 +/- 2 x 10^12 19F spins in a 1 pL volume, can be detected with a signal-to-noise ratio of 3 in 1 s integration. This represents nearly two orders of magnitude improvement in concentration sensitivity over previous NV and picoliter NMR studies.
arXiv comment7 pages, 6 figures (main text) + 11 pages, 7 figures, 5 tables (Supplemental)
References in corpus (20)
- Magnetometry with nitrogen-vacancy defects in diamond
- Universal dynamical decoupling of a single solid-state spin from a spin bath
- High nitrogen-vacancy density diamonds for magnetometry applications
- Chemical control of the charge state of nitrogen-vacancy centers in diamond
- Coherence of Nitrogen-Vacancy Electronic Spin Ensembles in Diamond
- Nanoscale NMR Spectroscopy and Imaging of Multiple Nuclear Species
- Detecting and polarizing nuclear spins with double resonance on a single electron spin
- Fabrication of Diamond Nanowires for Quantum Information Processing Applications
- Extending spin coherence times of diamond qubits by high temperature annealing
- High-Resolution Correlation Spectroscopy of 13C Spins Near a Nitrogen-Vacancy Center in Diamond
- Nanoscale nuclear magnetic resonance with a 1.9-nm-deep nitrogen-vacancy sensor
- Proton magnetic resonance imaging with a nitrogen-vacancy spin sensor
- NMR Technique for Determining the Depth of Shallow Nitrogen-Vacancy Centers in Diamond
- Scanning probe microscopy with chemical contrast by nanoscale nuclear magnetic resonance
- Probing molecular dynamics at the nanoscale via an individual paramagnetic center
- Optimizing a Dynamical Decoupling Protocol for Solid-State Electronic Spin Ensembles in Diamond
- Spurious harmonic response of multipulse quantum sensing sequences
- Detection of nuclear magnetic resonance with an anisotropic magnetoresistive sensor
- Boundary between the thermal and statistical polarization regimes in a nuclear spin ensemble
- Accelerated 2D magnetic resonance spectroscopy of single spins using matrix completion
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