169 citations
- Norwich Research ParkGB2 papers
- University of OxfordGB2 papers
- Adam Mickiewicz University in PoznańPL1 paper
- Imperial College LondonGB1 paper
- Institute for Atomic and Molecular PhysicsNL1 paper
- Max Planck SocietyDE1 paper
- Medawar Building for Pathogen ResearchGB1 paper
- Spanish National Cancer Research CentreES1 paper
- Stanford UniversityUS1 paper
- University of California, San FranciscoUS1 paper
- University of CambridgeGB1 paper
- University of SurreyGB1 paper
Showing 2009Show all
3 papers · 1 filter
q-bio.MN2009★ 31 cited
When it Pays to Rush: Interpreting Morphogen Gradients Prior to Steady-State
Timothy E Saunders, Martin Howard
During development, morphogen gradients precisely determine the position of gene expression boundaries despite the inevitable presence of fluctuations. Recent experiments suggest t…
q-bio.CB2009★ 93 cited
The role of spatial averaging in the precision of gene expression patterns
Thorsten Erdmann, Martin Howard, Pieter Rein ten Wolde
During embryonic development, differentiating cells respond via gene expression to positional cues from morphogen gradients. While gene expression is often highly erratic, embryoni…
q-bio.MN2009★ 53 cited
Morphogen Profiles Can Be Optimised to Buffer Against Noise
Timothy E Saunders, Martin Howard
Morphogen profiles play a vital role in biology by specifying position in embryonic development. However, the factors that influence the shape of a morphogen profile remain poorly…