457 citations
- InsermFR2 papers
- Institució Catalana de Recerca i Estudis AvançatsES2 papers
- Institute of Structural and Molecular BiologyGB2 papers
- University College LondonGB2 papers
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- Academia SinicaTW1 paper
- Babraham InstituteGB1 paper
- Barcelona Biomedical Research ParkES1 paper
- Biotechnologisches ZentrumDE1 paper
- Buck Institute for Research on AgingUS1 paper
- Center for Systems Biology DresdenDE1 paper
- Centre de Recherche en Cancérologie de LyonFR1 paper
8 papers
Universal scaling laws rule explosive growth inhuman cancers
Víctor M. Pérez-García, Gabriel F. Calvo, Jesús J. Bosque +24
Most physical and other natural systems are complex entities composed of a large number of interacting individual elements. It is a surprising fact that they often obey the so-call…
An expanded evaluation of protein function prediction methods shows an improvement in accuracy
Yuxiang Jiang, Tal Ronnen Oron, Wyatt T Clark +144
Background: The increasing volume and variety of genotypic and phenotypic data is a major defining characteristic of modern biomedical sciences. At the same time, the limitations i…
Integrating epigenomic data and 3D genomic structure with a new measure of chromatin assortativity
Vera Pancaldi, Enrique Carrillo-de-Santa-Pau, Biola Maria Javierre +5
Network analysis is a powerful way of modeling chromatin interactions. Assortativity is a network property used in social sciences to identify factors affecting how people establis…
A Boolean Gene Regulatory Model of heterosis and speciation
Peter M. F. Emmrich, Hannah E. Roberts, Vera Pancaldi
Modelling genetic phenomena affecting biological traits is important for the development of agriculture as it allows breeders to predict the potential of breeding for certain trait…
Late-replicating CNVs as a source of new genes
David Juan, Daniel Rico, Tomas Marques-Bonet +2
Asynchronous replication of the genome has been associated with different rates of point mutation and copy number variation (CNV) in human populations. Here, we explored if the bia…
Stress induces remodelling of yeast interaction and co-expression networks
Sonja Lehtinen, Francesc Xavier Marsellach, Sandra Codlin +6
Network analysis provides a powerful framework for the interpretation of genome-wide data. While static network approaches have proved fruitful, there is increasing interest in the…