169 citations
- Norwich Research ParkGB2 papers
- University of OxfordGB2 papers
- Adam Mickiewicz University in PoznańPL1 paper
- Imperial College LondonGB1 paper
- Institute for Atomic and Molecular PhysicsNL1 paper
- Max Planck SocietyDE1 paper
- Medawar Building for Pathogen ResearchGB1 paper
- Spanish National Cancer Research CentreES1 paper
- Stanford UniversityUS1 paper
- University of California, San FranciscoUS1 paper
- University of CambridgeGB1 paper
- University of SurreyGB1 paper
10 papers
Reassessment of the basis of cell size control based on analysis of cell-to-cell variability
Giuseppe Facchetti, Benjamin Knapp, Fred Chang +1
Fundamental mechanisms governing cell size control and homeostasis are still poorly understood. The relationship between sizes at division and birth in single cells is used as a me…
Centre-finding in E. coli and the role of mathematical modelling: past, present and future
Sean M. Murray, Martin Howard
We review the key role played by mathematical modelling in elucidating two centre-finding patterning systems in E. coli: midcell division positioning by the MinCDE system and DNA p…
Single-molecule imaging of DNA gyrase activity in living Escherichia coli
Mathew Stracy, Adam J. M. Wollman, Elzbieta Kaja +9
Bacterial DNA gyrase introduces negative supercoils into chromosomal DNA and relaxes positive supercoils introduced by replication and transiently by transcription. Removal of thes…
A Boolean Gene Regulatory Model of heterosis and speciation
Peter M. F. Emmrich, Hannah E. Roberts, Vera Pancaldi
Modelling genetic phenomena affecting biological traits is important for the development of agriculture as it allows breeders to predict the potential of breeding for certain trait…
Arabidopsis plants perform arithmetic division to prevent starvation at night
Antonio Scialdone, Sam T. Mugford, Doreen Feike +5
Photosynthetic starch reserves that accumulate in Arabidopsis leaves during the day decrease approximately linearly with time at night to support metabolism and growth. We find tha…
When it Pays to Rush: Interpreting Morphogen Gradients Prior to Steady-State
Timothy E Saunders, Martin Howard
During development, morphogen gradients precisely determine the position of gene expression boundaries despite the inevitable presence of fluctuations. Recent experiments suggest t…