most citedPopulation variability in the generation and thymic selection of T-cell repertoires

69 citations

researchers with a paper here
collaborating institutions

1 paper

q-bio.PE2020★ 69 cited

Population variability in the generation and thymic selection of T-cell repertoires

Zachary Sethna, Giulio Isacchini, Thomas Dupic +3

The diversity of T-cell receptor (TCR) repertoires is achieved by a combination of two intrinsically stochastic steps: random receptor generation by VDJ recombination, and selectio…