3.5k citations
Counting papers with at most 25 authors, so collaboration author lists do not stand in for the people here.
- University Hospital Schleswig-HolsteinDE21 papers
- Universität HamburgDE14 papers
- Ludwig-Maximilians-Universität MünchenDE11 papers
- University of OxfordGB10 papers
- Hamburg University of TechnologyDE9 papers
- University Medical Center Hamburg-EppendorfDE9 papers
- Worcester Polytechnic InstituteUS9 papers
- Christian-Albrechts-Universität zu KielDE8 papers
- Heidelberg UniversityDE8 papers
- University of KaiserslauternDE8 papers
- Fraunhofer Institute for Digital MedicineDE7 papers
- Institute of Applied Mathematics and MechanicsUA7 papers
24 papers · 1 filter
Stopping power monitoring during proton therapy by means of prompt gamma timing: first experimental results with a homogeneous phantom
Julius Werner, Francesco Pennazio, Piergiorgio Cerello +11
Proton therapy's full potential is limited by uncertainties that prevent optimal dose distribution. Monitoring techniques can reduce these uncertainties and enable adaptive treatme…
Analytical Model of Prompt Gamma Timing for Spatiotemporal Emission Reconstruction in Particle Therapy
Julius Werner, Malte Schmidt, Francesco Pennazio +4
Particle therapy relies on up-to-date knowledge of the stopping power of the patient tissues to deliver the prescribed dose distribution. The stopping power describes the average p…
Anatomically Informed GREIT Reconstruction: Improving EIT Imaging for Lung Monitoring
Maximilian Ludwig, Carolin M. Eichinger, Armin Sablewski +3
Objective: Time-difference electrical impedance tomography (EIT) is gaining widespread use for bedside lung monitoring in intensive care patients suffering from lung-related diseas…
First experimental test of a coded-mask gamma camera for proton therapy monitoring
Magdalena Kołodziej, Stephan Brons, Mikołaj Dubiel +15
Objective. The objective of the presented study was to evaluate the feasibility of a coded-mask (CM) gamma camera for real-time range verification in proton therapy, addressing the…
Characterization of the Clinically Approved MRI Tracer Resotran for Magnetic Particle Imaging in a Comparison Study
Fabian Mohn, Konrad Scheffler, Justin Ackers +7
Objective. The availability of magnetic nanoparticles with medical approval for human intervention is fundamental to the clinical translation of magnetic particle imaging (MPI). In…
System Characterization of a Human-Sized 3D Real-Time Magnetic Particle Imaging Scanner for Cerebral Applications
Florian Thieben, Fynn Foerger, Fabian Mohn +6
Since the initial patent in 2001, the Magnetic Particle Imaging (MPI) community has been striving to develop an MPI scanner suitable for human applications. Numerous contributions…
Current Methods for Hyperpolarized [1-13C]pyruvate MRI Human Studies
Peder EZ Larson, Jenna ML Bernard, James A Bankson +16
MRI with hyperpolarized (HP) 13C agents, also known as HP 13C MRI, can measure processes such as localized metabolism that is altered in numerous cancers, liver, heart, kidney dise…
Near-field coded-mask technique and its potential for proton therapy monitoring
Ronja Hetzel, Vitalii Urbanevych, Andreas Bolke +14
Objective. Prompt-gamma imaging encompasses several approaches for online monitoring of beam range or deposited dose distribution in proton therapy. We test one of the imaging tech…
Saline bolus for negative contrast perfusion imaging in magnetic particle imaging
Fabian Mohn, Miriam Exner, Patryk Szwargulski +3
Objective. Magnetic Particle Imaging (MPI) is capable of high temporal resolution measurements of the spatial distribution of magnetic nanoparticles and therefore well suited for p…
Spatial Sensitivity of ECG Electrode Placement
Andra Oltmann, Roman Kusche, Philipp Rostalski
The electrocardiogram (ECG) is a well-known technique used to diagnose cardiac diseases. To acquire the spatial signal characteristics from the thorax, multiple electrodes are comm…
Retinal blood flow imaging with combined full-field swept-source optical coherence tomography and laser Doppler holography
Léo Puyo, Hendrik Spahr, Clara Pfäffle +2
Full-field swept-source optical coherence tomography (FF-SS-OCT) and laser Doppler holography (LDH) are two holographic imaging techniques presenting unique capabilities for ophtha…
Laser Doppler holography of the anterior segment for blood flow imaging, eye tracking, and transparency assessment
Léo Puyo, Clémentine David, Rana Saad +6
Laser Doppler holography (LDH) is a full-field blood flow imaging technique able to reveal human retinal and choroidal blood flow with high temporal resolution. We here report on u…
A FPGA-Based Broadband EIT System for Complex Bioimpedance Measurements -- Design and Performance Estimation
Roman Kusche, Ankit Malhotra, Martin Ryschka +3
Electrical impedance tomography (EIT) is an imaging method that is able to estimate the electrical conductivity distribution of living tissue. This work presents a field programmab…
Zero roll-off retinal MHz-OCT using an FDML-Laser
Julian Klee, Jan Philip Kolb, Christin Grill +3
Optical coherence tomography (OCT) applications like ultra-widefield and full eye-length imaging are of high interest for various diagnostic purposes. In swept-source OCT these tec…
Towards combined optical coherence tomography and multi-spectral imaging with MHz a-scan rates for endoscopy
Madita Goeb, Tom Pfeiffer, Robert Huber
We demonstrate a preliminary setup of a combined MHz-OCT and RGB narrowband reflection microscope and investigate the performance of the new RGB branch and different display modes…
Virtual H&E Histology by Fiber-Based Picosecond Two-Photon Microscopy
Jan Philip Kolb, Daniel Weng, Hubertus Hakert +10
Two-Photon Microscopy (TPM) can provide three-dimensional morphological and functional contrast in vivo. Through proper staining, TPM can be utilized to create virtual, H&E equival…
An In-Ear Pulse Wave Velocity Measurement System Using Heart Sounds as Time Reference
Roman Kusche, Paula Klimach, Ankit Malhotra +2
Pulse wave measurements provide vital information in medical diagnosis. For this reason, a measurement system is developed for determining the transient time of the pulse wave betw…
Dynamic contrast in scanning microscopic OCT
Michael Münter, Malte vom Endt, Mario Pieper +7
While optical coherence tomography (OCT) provides a resolution down to 1 micrometer it has difficulties to visualize cellular structures due to a lack of scattering contrast. By ev…
Robust GPU-based Virtual Reality Simulation of Radio Frequency Ablations for Various Needle Geometries and Locations
Niclas Kath, Heinz Handels, Andre Mastmeyer
Purpose: Radio-frequency ablations play an important role in the therapy of malignant liver lesions. The navigation of a needle to the lesion poses a challenge for both the trainee…
A Multichannel Real-Time Bioimpedance Measurement Device for Pulse Wave Analysis
Roman Kusche, Paula Klimach, Martin Ryschka
Pulse wave analysis is an important method used to gather information about the cardiovascular system. Instead of detecting the pulse wave via pressure sensors, bioimpedance measur…
Moving Table Magnetic Particle Imaging: A stepwise approach preserving high spatio-temporal resolution
Patryk Szwargulski, Nadine Gdaniec, Matthias Graeser +5
Magnetic Particle Imaging (MPI) is a highly sensitive imaging method that enables the visualization of magnetic tracer materials with a temporal resolution of more than 46 volumes…
Flexible A-scan rate MHz OCT: Computational downscaling by coherent averaging
Tom Pfeiffer, Wolfgang Wieser, Thomas Klein +4
In order to realize fast OCT-systems with adjustable line rate, we investigate averaging of image data from an FDML based MHz-OCT-system. The line rate can be reduced in software a…
In vivo optical imaging of physiological responses to photostimulation in human photoreceptors
Dierck Hillmann, Hendrik Spahr, Clara Pfäffle +3
Non-invasive functional imaging of molecular and cellular processes of vision is expected to have immense impact on research and clinical diagnostics. Although suitable intrinsic o…
MDF: Magnetic Particle Imaging Data Format
Tobias Knopp, Thilo Viereck, Gael Bringout +7
Magnetic particle imaging (MPI) is a tomographic method to determine the spatio-temporal distribution of magnetic nanoparticles. In this document, a file format for the standardize…