activity
20142020
most citedTime-Encoded Raman: Fiber-based, hyperspectral, broadband stimulated Raman microscopy

101 citations · 180 across the 14 of their papers we have counts for

collaborators

14 papers

physics.optics2020★ 9 cited

Intensity Pattern Types in Broadband Fourier Domain Mode-Locked (FDML) Lasers Operating Beyond the Ultra-Stable Regime

Mark Schmidt, Christin Grill, Simon Lotz +3

We report on the formation of various intensity pattern types in detuned Fourier domain mode-locked (FDML) lasers and identify the corresponding operating conditions. Such patterns…

physics.med-ph2020

Zero roll-off retinal MHz-OCT using an FDML-Laser

Julian Klee, Jan Philip Kolb, Christin Grill +3

Optical coherence tomography (OCT) applications like ultra-widefield and full eye-length imaging are of high interest for various diagnostic purposes. In swept-source OCT these tec…

physics.med-ph2020★ 1 cited

Towards combined optical coherence tomography and multi-spectral imaging with MHz a-scan rates for endoscopy

Madita Goeb, Tom Pfeiffer, Robert Huber

We demonstrate a preliminary setup of a combined MHz-OCT and RGB narrowband reflection microscope and investigate the performance of the new RGB branch and different display modes…

physics.med-ph2020★ 2 cited

Virtual H&E Histology by Fiber-Based Picosecond Two-Photon Microscopy

Jan Philip Kolb, Daniel Weng, Hubertus Hakert +10

Two-Photon Microscopy (TPM) can provide three-dimensional morphological and functional contrast in vivo. Through proper staining, TPM can be utilized to create virtual, H&E equival…

physics.optics2020★ 17 cited

Self-Stabilization Mechanism in Ultra-Stable Fourier Domain Mode-Locked (FDML) Lasers

Mark Schmidt, Tom Pfeiffer, Christin Grill +2

Understanding the dynamics of Fourier domain mode-locked (FDML) lasers is crucial for determining physical coherence limits, and for finding new superior methods for experimental r…

physics.optics2018

Wavelength agile multi-photon microscopy with a fiber amplified diode laser

Matthias Eibl, Daniel Weng, Hubertus Hakert +5

Multi-photon microscopy is a powerful tool in biomolecular research. Less complex and more cost effective excitation light sources will make this technique accessible to a broader…

physics.ins-det2018★ 5 cited

Two-photon-excited fluorescence (TPEF) and fluorescence lifetime imaging (FLIM) with sub-nanosecond pulses and a high analog bandwidth signal detection

Matthias Eibl, Sebastian Karpf, Hubertus Hakert +2

Two-photon excited fluorescence (TPEF) microscopy and fluorescence lifetime imaging (FLIM) are powerful imaging techniques in bio-molecular science. The need for elaborate light so…

physics.ins-det2018★ 10 cited

Analysis of FDML lasers with meter range coherence

Tom Pfeiffer, Wolfgang Draxinger, Wolfgang Wieser +3

FDML lasers provide sweep rates in the MHz range at wide optical bandwidths, making them ideal sources for high speed OCT. Recently, at lower speed, ultralong-range swept-source OC…

physics.optics2018

Pulse-to-pulse wavelength switchting of diode based fiber laser for multi-color multi-photon imaging

Matthias Eibl, Sebastian Karpf, Hubertus Hakert +3

We present an entirely fiber based laser source for non-linear imaging with a novel approach for multi-color excitation. The high power output of an actively modulated and amplifie…

physics.optics2018★ 12 cited

Shot-Noise limited Time-encoded (TICO) Raman spectroscopy

Sebastian Karpf, Matthias Eibl, Wolfgang Wieser +2

Raman scattering, an inelastic scattering mechanism, provides information about molecular excitation energies and can be used to identify chemical compounds. Albeit being a powerfu…

physics.optics2018★ 10 cited

Efficient simulation of the swept-waveform polarization dynamics in fiber spools and Fourier domain mode-locked (FDML) lasers

Christian Jirauschek, Robert Huber

We present a theoretical model and its efficient numerical implementation for the simulation of wavelength-swept waveform propagation in fiber systems such as Fourier domain mode-l…

physics.med-ph2016★ 4 cited

Flexible A-scan rate MHz OCT: Computational downscaling by coherent averaging

Tom Pfeiffer, Wolfgang Wieser, Thomas Klein +4

In order to realize fast OCT-systems with adjustable line rate, we investigate averaging of image data from an FDML based MHz-OCT-system. The line rate can be reduced in software a…

physics.optics2016★ 9 cited

Megahertz FDML Laser with up to 143nm Sweep Range for Ultrahigh Resolution OCT at 1050nm

Jan Philip Kolb, Thomas Klein, Mattias Eibl +3

We present a new design of a Fourier Domain Mode Locked laser (FDML laser), which provides a new record in sweep range at ~1um center wavelength: At the fundamental sweep rate of 2…

physics.optics2014★ 101 cited

Time-Encoded Raman: Fiber-based, hyperspectral, broadband stimulated Raman microscopy

Sebastian Karpf, Matthias Eibl, Wolfgang Wieser +2

Raman sensing and Raman microscopy are amongst the most specific optical technologies to identify the chemical compounds of unknown samples, and to enable label-free biomedical ima…