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6 papers · 1 filter
A Metric for Evaluating Neural Input Representation in Supervised Learning Networks
Richard R Carrillo, Francisco Naveros, Eduardo Ros +1
Supervised learning has long been attributed to several feed-forward neural circuits within the brain, with attention being paid to the cerebellar granular layer. The focus of this…
Bioconjugated oligonucleotides: recent developments and thera-eutic applications
Sébastien Benizri, Arnaud Gissot, Andrew Martin +3
Oligonucleotide-based agents have the potential to treat or cure almost any disease, and are one of the key therapeutic drug classes of the future. Bioconjugated oligonucleotides,…
Neurogenetics of the Human Adenosine Receptor Genes: Genetic Structures and Involvement in Brain Diseases
Vincent Huin, Claire-Marie Dhaenens, Mégane Homa +3
Adenosine receptors are G-protein-coupled receptors involved in a wide range of physiological and pathological phenomena in most mammalian systems. All four receptors are widely ex…
Differentiation of neural-type cells on multi-scale ordered collagen-silica bionanocomposites
Nicolas Debons, Dounia Dems, Christophe Hélary +7
Cells respond to biophysical and biochemical signals. We developed a composite filament from collagen and silica particles modified to interact with collagen and/or present a lamin…
User-in-the-loop Adaptive Intent Detection for Instructable Digital Assistant
Nicolas Lair, Clément Delgrange, David Mugisha +3
People are becoming increasingly comfortable using Digital Assistants (DAs) to interact with services or connected objects. However, for non-programming users, the available possib…
The double dealing of cyclin D1
Guergana Tchakarska, Brigitte Sola
The cell cycle is tightly regulated by cyclins and their catalytic moieties, the cyclin-dependent kinases (CDKs). Cyclin D1, in association with CDK4/6, acts as a mitogenic sensor…