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57 papers · 1 filter
Multiplex core-periphery organization of the human connectome
Federico Battiston, Jeremy Guillon, Mario Chavez +2
The behavior of many complex systems is determined by a core of densely interconnected units. While many methods are available to identify the core of a network when connections be…
Increased hepatic PDGF-AA signaling mediates liver insulin resistance in obesity associated type 2 diabetes
Amar Abderrahmani, Loic Yengo, Robert Caiazzo +35
Type 2 diabetes (T2D) is closely linked with non-alcoholic fatty liver disease (NAFLD) and hepatic insulin resistance, but the involved mechanisms are still elusive. Using DNA meth…
Single-particle Mass Spectrometry with arrays of frequency-addressed nanomechanical resonators
Eric Sage, Marc Sansa, Shawn Fostner +12
One of the main challenges to overcome to perform nanomechanical Mass Spectrometry (NEMS-MS) analysis in a practical time frame stems from the size mismatch between the analyte bea…
Tensile rupture of medial arterial tissue studied by X-ray micro-tomography on stained samples
Clémentine Helfenstein-Didier, Damien Taïnoff, Julien Viville +3
Detailed characterization of damage and rupture mechanics of arteries is one the current challenges in vascular biomechanics, which requires developing suitable experimental approa…
Development and cytotoxic response of two proliferative MDA- MB-231 and non-proliferative SUM1315 three-dimensional cell culture models of triple-negative basal-like breast cancer cell lines
Clémence Dubois, Dufour Robin, Daumar Pierre +6
Triple-Negative Basal-Like tumors, representing 15 to 20% of breast cancers, are very aggressive and with poor prognosis. Targeted therapies have been developed extensively in prec…
Parallel transport in shape analysis: a scalable numerical scheme
Maxime Louis, Alexandre Bône, Benjamin Charlier +1
The analysis of manifold-valued data requires efficient tools from Riemannian geometry to cope with the computational complexity at stake. This complexity arises from the always-in…