output
20222025
most citedDiffusion Probabilistic Models beat GANs on Medical Images

215 citations

19 papers

q-bio.QM2025

Gut decisions based on the liver: A radiomics approach to boost colorectal cancer screening

Anna Hinterberger, Jonas Bohn, Dasha Trofimova +13

Non-invasive colorectal cancer (CRC) screening represents a key opportunity to improve colonoscopy participation rates and reduce CRC mortality. This study explores the potential o…

cs.CV2025

Hallucination Filtering in Radiology Vision-Language Models Using Discrete Semantic Entropy

Patrick Wienholt, Sophie Caselitz, Robert Siepmann +6

To determine whether using discrete semantic entropy (DSE) to reject questions likely to generate hallucinations can improve the accuracy of black-box vision-language models (VLMs)…

cs.CV2025

Resolution scaling governs DINOv3 transfer performance in chest radiograph classification

Soroosh Tayebi Arasteh, Mina Shaigan, Christiane Kuhl +3

Self-supervised learning (SSL) has improved visual representation learning, but its value in chest radiography remains uncertain. DINOv3 extends earlier SSL models through Gram-anc…

cs.CV2025

Federated Learning for Surgical Vision in Appendicitis Classification: Results of the FedSurg EndoVis 2024 Challenge

Max Kirchner, Hanna Hoffmann, Alexander C. Jenke +16

Developing generalizable surgical AI requires multi-institutional data, yet privacy constraints preclude direct data sharing, making Federated Learning (FL) a natural candidate. It…

cs.CV2025★ 2 cited

MedicalPatchNet: A Patch-Based Self-Explainable AI Architecture for Chest X-ray Classification

Patrick Wienholt, Christiane Kuhl, Jakob Nikolas Kather +2

Deep neural networks excel in radiological image classification but frequently suffer from poor interpretability, limiting clinical acceptance. We present MedicalPatchNet, an inher…

cs.LG2025★ 1 cited

Generating Reliable Synthetic Clinical Trial Data: The Role of Hyperparameter Optimization and Domain Constraints

Waldemar Hahn, Jan-Niklas Eckardt, Christoph Röllig +3

The generation of synthetic clinical trial data offers a promising approach to mitigating privacy concerns and data accessibility limitations in medical research. However, ensuring…

cs.CV2025★ 2 cited

Enhanced Anomaly Detection for Capsule Endoscopy Using Ensemble Learning Strategies

Julia Werner, Christoph Gerum, Jorg Nick +4

Capsule endoscopy is a method to capture images of the gastrointestinal tract and screen for diseases which might remain hidden if investigated with standard endoscopes. Due to the…

eess.IV2024★ 20 cited

Medical Slice Transformer: Improved Diagnosis and Explainability on 3D Medical Images with DINOv2

Gustav Müller-Franzes, Firas Khader, Robert Siepmann +4

MRI and CT are essential clinical cross-sectional imaging techniques for diagnosing complex conditions. However, large 3D datasets with annotations for deep learning are scarce. Wh…

cs.CL2024★ 25 cited

Large Language Models-Enabled Digital Twins for Precision Medicine in Rare Gynecological Tumors

Jacqueline Lammert, Nicole Pfarr, Leonid Kuligin +16

Rare gynecological tumors (RGTs) present major clinical challenges due to their low incidence and heterogeneity. The lack of clear guidelines leads to suboptimal management and poo…

cs.CL2024★ 27 cited

RadioRAG: Online Retrieval-augmented Generation for Radiology Question Answering

Soroosh Tayebi Arasteh, Mahshad Lotfinia, Keno Bressem +7

Large language models (LLMs) often generate outdated or inaccurate information based on static training datasets. Retrieval-augmented generation (RAG) mitigates this by integrating…

cs.CL2024★ 23 cited

Superhuman performance in urology board questions by an explainable large language model enabled for context integration of the European Association of Urology guidelines: the UroBot study

Martin J. Hetz, Nicolas Carl, Sarah Haggenmüller +4

Large Language Models (LLMs) are revolutionizing medical Question-Answering (medQA) through extensive use of medical literature. However, their performance is often hampered by out…

cs.CV2023★ 7 cited

Benchmarking Pathology Feature Extractors for Whole Slide Image Classification

Georg Wölflein, Dyke Ferber, Asier R. Meneghetti +6

Weakly supervised whole slide image classification is a key task in computational pathology, which involves predicting a slide-level label from a set of image patches constituting…

cs.LG2023★ 112 cited

Large Language Models Streamline Automated Machine Learning for Clinical Studies

Soroosh Tayebi Arasteh, Tianyu Han, Mahshad Lotfinia +4

A knowledge gap persists between machine learning (ML) developers (e.g., data scientists) and practitioners (e.g., clinicians), hampering the full utilization of ML for clinical da…

eess.IV2023★ 34 cited

Enhancing Network Initialization for Medical AI Models Using Large-Scale, Unlabeled Natural Images

Soroosh Tayebi Arasteh, Leo Misera, Jakob Nikolas Kather +2

Pre-training datasets, like ImageNet, have become the gold standard in medical image analysis. However, the emergence of self-supervised learning (SSL), which leverages unlabeled d…

eess.IV2023★ 151 cited

The Multi-modality Cell Segmentation Challenge: Towards Universal Solutions

Jun Ma, Ronald Xie, Shamini Ayyadhury +37

Cell segmentation is a critical step for quantitative single-cell analysis in microscopy images. Existing cell segmentation methods are often tailored to specific modalities or req…

eess.IV2023★ 8 cited

Using Multiple Dermoscopic Photographs of One Lesion Improves Melanoma Classification via Deep Learning: A Prognostic Diagnostic Accuracy Study

Achim Hekler, Roman C. Maron, Sarah Haggenmüller +28

Background: Convolutional neural network (CNN)-based melanoma classifiers face several challenges that limit their usefulness in clinical practice. Objective: To investigate the im…

eess.IV2023★ 18 cited

Fibroglandular Tissue Segmentation in Breast MRI using Vision Transformers -- A multi-institutional evaluation

Gustav Müller-Franzes, Fritz Müller-Franzes, Luisa Huck +9

Accurate and automatic segmentation of fibroglandular tissue in breast MRI screening is essential for the quantification of breast density and background parenchymal enhancement. I…

eess.IV2022★ 215 cited

Diffusion Probabilistic Models beat GANs on Medical Images

Gustav Müller-Franzes, Jan Moritz Niehues, Firas Khader +8

The success of Deep Learning applications critically depends on the quality and scale of the underlying training data. Generative adversarial networks (GANs) can generate arbitrary…

cs.LG2022★ 28 cited

Collaborative Training of Medical Artificial Intelligence Models with non-uniform Labels

Soroosh Tayebi Arasteh, Peter Isfort, Marwin Saehn +6

Due to the rapid advancements in recent years, medical image analysis is largely dominated by deep learning (DL). However, building powerful and robust DL models requires training…