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most citedCellular network entropy as the energy potential in Waddington's differentiation landscape

157 citations

Showing q-bio.QMShow all

5 papers · 1 filter

q-bio.QM2022★ 34 cited

Slim: interoperable slide microscopy viewer and annotation tool for imaging data science and computational pathology

Chris Gorman, Davide Punzo, Igor Octaviano +6

The exchange of large and complex slide microscopy imaging data in biomedical research and pathology practice is impeded by a lack of data standardization and interoperability, whi…

q-bio.QM2016★ 20 cited

Time Dependent Saddle Node Bifurcation: Breaking Time and the Point of No Return in a Non-Autonomous Model of Critical Transitions

Jeremiah Li, Felix X. -F. Ye, Hong Qian +1

There is a growing awareness that catastrophic phenomena in biology and medicine can be mathematically represented in terms of saddle-node bifurcations. In particular, the term `ti…

q-bio.QM2013★ 20 cited

Multi-study Integration of Brain Cancer Transcriptomes Reveals Organ-Level Molecular Signatures

Jaeyun Sung, Pan-Jun Kim, Shuyi Ma +6

We utilized abundant transcriptomic data for the primary classes of brain cancers to study the feasibility of separating all of these diseases simultaneously based on molecular dat…

q-bio.QM2007★ 18 cited

ProbCD: enrichment analysis accounting for categorization uncertainty

Ricardo Vêncio, Ilya Shmulevich

As in many other areas of science, systems biology makes extensive use of statistical association and significance estimates in contingency tables, a type of categorical data analy…

q-bio.QM2007★ 14 cited

Simcluster: clustering enumeration gene expression data on the simplex space

Ricardo ZN Vêncio, Leonardo Varuzza, Carlos AB Pereira +2

Transcript enumeration methods such as SAGE, MPSS, and sequencing-by-synthesis EST ``digital northern'', are important high-throughput techniques for digital gene expression measur…