output
20132026
most citedFederated Learning Enables Big Data for Rare Cancer Boundary Detection

390 citations

17 papers

cs.CV2026

Towards Trustworthy AI for Glioma Diagnosis: A Task-Aware Evaluation of Uncertainty Quantification

Gonzalo Esteban Mosquera Rojas, Sebastian R. van der Voort, Carolin M. Pirkl +3

Uncertainty Quantification (UQ) is a key requirement for trustworthy AI in high-stakes medical image analysis. In this work, we evaluate UQ in a multi-task Deep Learning framework…

stat.ME2025

Treatment effect estimation by comparing observed and predicted outcomes: conditions for valid inference and practical illustration

Lotta M. Meijerink, Artuur M. Leeuwenberg, Jungyeon Choi +6

Prediction models developed before the introduction of a new treatment may be used to estimate treatment effects of newly introduced treatments. One approach, known as model-based…

eess.IV2025★ 2 cited

The 4D Human Embryonic Brain Atlas: spatiotemporal atlas generation for rapid anatomical changes

Wietske A. P. Bastiaansen, Melek Rousian, Anton H. J. Koning +4

Early brain development is crucial for lifelong neurodevelopmental health. However, current clinical practice offers limited knowledge of normal embryonic brain anatomy on ultrasou…

eess.SY2024★ 6 cited

Constraint-adaptive MPC for large-scale systems: Satisfying state constraints without imposing them

S. A. N. Nouwens, B. de Jager, M. M. Paulides +1

Model Predictive Control (MPC) is a successful control methodology, which is applied to increasingly complex systems. However, real-time feasibility of MPC can be challenging for c…

eess.SY2024★ 2 cited

Accelerating soft-constrained MPC for linear systems through online constraint removal

S. A. N. Nouwens, M. M. Paulides, W. P. M. H. Heemels

Optimization-based controllers, such as Model Predictive Control (MPC), have attracted significant research interest due to their intuitive concept, constraint handling capabilitie…

eess.SY2024

Approximate Kalman filtering for large-scale systems with an application to hyperthermia cancer treatments

S. A. N. Nouwens, M. M. Paulides, W. P. M. H. Heemels

Accurate state estimates are required for increasingly complex systems, to enable, for example, feedback control. However, available state estimation schemes are not necessarily re…

eess.SY2024★ 6 cited

Constraint Removal for MPC with Performance Preservation and a Hyperthermia Cancer Treatment Case Study

S. A. N. Nouwens, B. de Jager, M. M. Paulides +1

Model predictive control (MPC) is an optimization-based control strategy with broad industrial adoption. Unfortunately, the required computation time to solve the receding-horizon…

cs.AI2024★ 20 cited

AI in radiological imaging of soft-tissue and bone tumours: a systematic review evaluating against CLAIM and FUTURE-AI guidelines

Douwe J. Spaanderman, Matthew Marzetti, Xinyi Wan +13

Soft-tissue and bone tumours (STBT) are rare, diagnostically challenging lesions with variable clinical behaviours and treatment approaches. This systematic review provides an over…

cs.CV2024★ 50 cited

A large-scale multicenter breast cancer DCE-MRI benchmark dataset with expert segmentations

Lidia Garrucho, Kaisar Kushibar, Claire-Anne Reidel +30

Artificial Intelligence (AI) research in breast cancer Magnetic Resonance Imaging (MRI) faces challenges due to limited expert-labeled segmentations. To address this, we present a…

cs.CV2024★ 4 cited

Self-Contrastive Weakly Supervised Learning Framework for Prognostic Prediction Using Whole Slide Images

Saul Fuster, Farbod Khoraminia, Julio Silva-Rodríguez +7

We present a pioneering investigation into the application of deep learning techniques to analyze histopathological images for addressing the substantial challenge of automated pro…

eess.IV2024★ 9 cited

Minimally Interactive Segmentation of Soft-Tissue Tumors on CT and MRI using Deep Learning

Douwe J. Spaanderman, Martijn P. A. Starmans, Gonnie C. M. van Erp +9

Segmentations are crucial in medical imaging to obtain morphological, volumetric, and radiomics biomarkers. Manual segmentation is accurate but not feasible in the radiologist's cl…

cs.CV2023★ 23 cited

Vision Transformers for Small Histological Datasets Learned through Knowledge Distillation

Neel Kanwal, Trygve Eftestol, Farbod Khoraminia +2

Computational Pathology (CPATH) systems have the potential to automate diagnostic tasks. However, the artifacts on the digitized histological glass slides, known as Whole Slide Ima…

math.OC2023★ 22 cited

Constraint-Adaptive MPC for linear systems: A system-theoretic framework for speeding up MPC through online constraint removal

S. A. N. Nouwens, M. M. Paulides, W. P. M. H. Heemels

Reducing the computation time of model predictive control (MPC) is important, especially for systems constrained by many state constraints. In this paper, we propose a new online c…

cs.LG2022★ 390 cited

Federated Learning Enables Big Data for Rare Cancer Boundary Detection

Sarthak Pati, Ujjwal Baid, Brandon Edwards +276

Although machine learning (ML) has shown promise in numerous domains, there are concerns about generalizability to out-of-sample data. This is currently addressed by centrally shar…

eess.IV2020★ 35 cited

Differential diagnosis and molecular stratification of gastrointestinal stromal tumors on CT images using a radiomics approach

Martijn P. A. Starmans, Milea J. M. Timbergen, Melissa Vos +10

Distinguishing gastrointestinal stromal tumors (GISTs) from other intra-abdominal tumors and GISTs molecular analysis is necessary for treatment planning, but challenging due to it…

physics.med-ph2020★ 3 cited

Dose Prediction with Deep Learning for Prostate Cancer Radiation Therapy: Model Adaptation to Different Treatment Planning Practices

Roya Norouzi Kandalan, Dan Nguyen, Nima Hassan Rezaeian +5

This work aims to study the generalizability of a pre-developed deep learning (DL) dose prediction model for volumetric modulated arc therapy (VMAT) for prostate cancer and to adap…

physics.med-ph2013★ 10 cited

The 'nanobig rods' class of gold nanorods: optimized dimensions for improved in vivo therapeutic and imaging efficacy

Constantin Ungureanu, Gerben A. Koning, Ton G. van Leeuwen +1

Currently, gold nanorods can be synthesized in a wide range of sizes. However, for intended biological applications gold nanorods with approximate dimensions 50 nm x 15 nm are used…