4.8k citations
Counting papers with at most 25 authors, so collaboration author lists do not stand in for the people here.
- The University of MelbourneAU18 papers
- Royal Children's HospitalAU16 papers
- Peter Doherty InstituteAU4 papers
- Monash UniversityAU3 papers
- The Royal Melbourne HospitalAU3 papers
- Université Paris-SaclayFR3 papers
- Brigham and Women's HospitalUS2 papers
- CEA Paris-SaclayFR2 papers
- Centre National de la Recherche ScientifiqueFR2 papers
- Commissariat à l'Énergie Atomique et aux Énergies AlternativesFR2 papers
- Deakin UniversityAU2 papers
- Eindhoven University of TechnologyNL2 papers
24 papers
Millennium Pathways for Tractography: 40 grand challenges to shape the future of tractography
Maxime Descoteaux, Kurt G. Schilling, Dogu Baran Aydogan +44
In the spirit of the historic Millennium Prize Problems that heralded a new era for mathematics, the newly formed International Society for Tractography (IST) has launched the Mill…
Small brains but big challenges: white matter tractography in early life samples
Jessica Dubois, Mareike Grotheer, Joseph Yuan-Mou Yang +3
In the human brain, white matter development is a complex and long-lasting process involving intermingling micro-and macrostructural mechanisms, such as fiber growth, pruning and m…
Electro-Optic Modulator source as sample-free calibrator and frequency stabilizer for Brillouin Microscopy
Claudia Testi, Emanuele Pontecorvo, Chiara Bartoli +5
Brillouin Microscopy is a novel label-free optical technique that enables the measurement of a material's mechanical properties at the sub-micron scale in a non-invasive and non-co…
MICCAI-CDMRI 2023 QuantConn Challenge Findings on Achieving Robust Quantitative Connectivity through Harmonized Preprocessing of Diffusion MRI
Nancy R. Newlin, Kurt Schilling, Serge Koudoro +33
White matter alterations are increasingly implicated in neurological diseases and their progression. International-scale studies use diffusion-weighted magnetic resonance imaging (…
Harmonizing Flows: Leveraging normalizing flows for unsupervised and source-free MRI harmonization
Farzad Beizaee, Gregory A. Lodygensky, Chris L. Adamson +5
Lack of standardization and various intrinsic parameters for magnetic resonance (MR) image acquisition results in heterogeneous images across different sites and devices, which adv…
A novel optical assay system for bilirubin concentration measurement in whole blood
Jean Pierre Ndabakuranye, Anushi E. Rajapaksa, Genia Burchall +3
As a biomarker for liver disease, bilirubin has been utilized in prognostic scoring systems for cirrhosis. While laboratory-based methods are used to determine bilirubin levels in…
On the distribution of isometric log-ratio transformations under extra-multinomial count data
Noora Kartiosuo, Joni Virta, Jaakko Nevalainen +2
Compositional data arise when count observations are normalised into proportions adding up to unity. To allow use of standard statistical methods, compositional proportions can be…
Handling missing data when estimating causal effects with Targeted Maximum Likelihood Estimation
S. Ghazaleh Dashti, Katherine J. Lee, Julie A. Simpson +3
Targeted Maximum Likelihood Estimation (TMLE) is increasingly used for doubly robust causal inference, but how missing data should be handled when using TMLE with data-adaptive app…
Comparative Analysis of Packages and Algorithms for the Analysis of Spatially Resolved Transcriptomics Data
Natalie Charitakis, Mirana Ramialison, Hieu T. Nim
The technology to generate Spatially Resolved Transcriptomics (SRT) data is rapidly being improved and applied to investigate a variety of biological tissues. The ability to interr…
Variant interpretation using population databases: lessons from gnomAD
Sanna Gudmundsson, Moriel Singer-Berk, Nicholas A. Watts +7
Reference population databases are an essential tool in variant and gene interpretation. Their use guides the identification of pathogenic variants amidst the sea of benign variati…
From climate change to pandemics: decision science can help scientists have impact
Christopher M. Baker, Patricia T. Campbell, Iadine Chades +8
Scientific knowledge and advances are a cornerstone of modern society. They improve our understanding of the world we live in and help us navigate global challenges including emerg…
Contextual Stress and Maternal Sensitivity: A Meta-Analytic Review of Stress Associations with the Maternal Behavior Q-Sort in Observational Studies
Anna Tudehope Booth, Jacqui Macdonald, George Youssef
Maternal sensitivity is a modifiable determinant of infant attachment security and a precursor to optimal child development. Contextual stressors undermine sensitivity, but researc…
Mathematical modelling indicates that lower activity of the haemostatic system in neonates is primarily due to lower prothrombin concentration
Ivo Siekmann, Stefan Bjelosevic, Kerry Landman +3
Haemostasis is governed by a highly complex system of interacting proteins. Due to the central role of thrombin, thrombin generation and specifically the thrombin generation curve…
Sequential infection experiments for quantifying innate and adaptive immunity during influenza infection
Ada W. C. Yan, Sophie G. Zaloumis, Julie A. Simpson +1
Laboratory models are often used to understand the interaction of related pathogens via host immunity. For example, recent experiments where ferrets were exposed to two influenza s…
A mechanistic model quantifies artemisinin-induced parasite growth retardation in blood-stage Plasmodium falciparum infection
Pengxing Cao, Nectarios Klonis, Sophie Zaloumis +6
Falciparum malaria is a major parasitic disease causing widespread morbidity and mortality globally. Artemisinin derivatives---the most effective and widely-used antimalarials that…
A biological model of scabies infection dynamics and treatment explains why mass drug administration does not lead to elimination
M. Lydeamore, P. T. Campbell, D. G. Regan +7
Despite a low global prevalence, infections with Sarcoptes scabiei, or scabies, are still common in remote communities such as in northern Australia and the Solomon Islands. Mass d…
Bayesian modelling of lung function data from multiple-breath washout tests
Robert K. Mahar, John B. Carlin, Sarath Ranganathan +3
Paediatric respiratory researchers have widely adopted the multiple-breath washout (MBW) test because it allows assessment of lung function in unsedated infants and is well suited…
A dynamic stress model explains the delayed drug effect in artemisinin treatment of Plasmodium falciparum
Pengxing Cao, Nectarios Klonis, Sophie Zaloumis +8
Artemisinin resistance constitutes a major threat to the continued success of control programs for malaria. With alternative antimalarial drugs not yet available, improving our und…
On the role of T cells in determining recovery time from influenza virus infection
Pengxing Cao, Zhongfang Wang, Ada W. C. Yan +5
Myriad experiments have identified an important role for T cell response mechanisms in determining recovery from influenza A virus infection. Animal models of influenza…
Periodic solutions in an SIRWS model with immune boosting and cross-immunity
Tiffany Leung, Barry D. Hughes, Federico Frascoli +1
Incidence of whooping cough, an infection caused by Bordetella pertussis and Bordetella parapertussis, has been on the rise since the 1980s in many countries. Immunological interac…
Modelling cross-reactivity and memory in the cellular adaptive immune response to influenza infection in the host
Ada W. C. Yan, Pengxing Cao, Jane M. Heffernan +5
The cellular adaptive immune response plays a key role in resolving influenza infection. Experiments where individuals are successively infected with different strains within a sho…
Robust hyperparameter estimation protects against hypervariable genes and improves power to detect differential expression
Belinda Phipson, Stanley Lee, Ian J. Majewski +2
One of the most common analysis tasks in genomic research is to identify genes that are differentially expressed (DE) between experimental conditions. Empirical Bayes (EB) statisti…
What Is Meant by "Missing at Random"?
Shaun Seaman, John Galati, Dan Jackson +1
The concept of missing at random is central in the literature on statistical analysis with missing data. In general, inference using incomplete data should be based not only on obs…
Bayesian Test for Colocalisation Between Pairs of Genetic Association Studies Using Summary Statistics
Claudia Giambartolomei, Damjan Vukcevic, Eric E. Schadt +4
Genetic association studies, in particular the genome-wide association study design, have provided a wealth of novel insights into the aetiology of a wide range of human diseases a…